Creatine Kinase, Not Creatinine Kinase

Jefferson, James W.; Aga, Vimal M.

doi:10.1097/01.jcp.0000096249.95165.e5

Journal of Clinical Psychopharmacology

2003

DOI: 10.1097/01.jcp.0000096249.95165.e5

|View full text |Cite

Creatine Kinase, Not Creatinine Kinase

James W. Jefferson

Vimal M. Aga

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mistake of referring to creatine kinase as creatinine kinase is common in the medical literature [ [3] , [4] , [5] , [6] ]. A plea for precision in the naming of this enzyme was published in 2003 [ 7 ]; it is time to echo this plea in order to stop the spread of the creatine kinase misspelling epidemic.…”

mentioning

confidence: 99%

CK – What does it stand for?

Flynn

2021

The American Journal of Emergency Medicine

View full text Add to dashboard Cite

In a recent edition of the American Journal of Emergency Medicine, Chan et al. describe two cases of weakness and elevated "creatinine kinase" (sic) as the initial presentation of coronavirus disease 2019 (COVID-19) [1]. The reference to "creatinine kinase" in the article title is repeated in the keywords and abstract, although in the main text the enzyme is simply referred to as "CK". Rather than creatinine kinase, presumably the authors were instead referring to the enzyme creatine kinase. Creatine kinase catalyses the phosphorylation of creatine to phosphocreatine, is frequently measured as a marker of muscle damage, and is commonly abbreviated as "CK" [2]. Creatinine is neither a product nor substrate for creatine kinase, and is instead formed from creatine and phosphocreatine via non-enzymatic reactions. It is likely that most readers understood the authors as they intended, and did not erroneously conclude that a novel "creatinine kinase" assay is a potential marker of COVID-19 infection. The authors claim that these are the first two reported cases of COVID-19 presenting initially as an isolated muscle weakness with increased CK. The spelling error does raise doubts as to whether, in reaching that conclusion, the authors used the correct terminology for creatine kinase in their literature search. The mistake of referring to creatine kinase as creatinine kinase is common in the medical literature [3-6]. A plea for precision in the naming of this enzyme was published in 2003 [7]; it is time to echo this plea in order to stop the spread of the creatine kinase misspelling epidemic.

show abstract

mentioning

confidence: 99%

CK – What does it stand for?

Flynn

2021

The American Journal of Emergency Medicine

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Creatine Kinase, Not Creatinine Kinase

Cited by 1 publication

References 2 publications

CK – What does it stand for?

CK – What does it stand for?

Contact Info

Product

Resources

About