1983
DOI: 10.1016/0165-6147(83)90422-4
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Creativity in drug research II

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1986
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“…Another example comes from the work of Cowan in hypothesising an explanation for some drug-induced hallucinations, sparked off by the analogy between the simple geometric patterns seen in the early stages of hallucination, and similar patterns seen in fluid convection [36]. The initial concept of two histamine receptors, which provoked work leading to the discovery of the highly important H2 receptor antagonist drugs, was sparked by analogies with other substances acting at two sites with different effects [38]. Many other examples may be given.…”
Section: Specific Aspectsmentioning
confidence: 99%
“…Another example comes from the work of Cowan in hypothesising an explanation for some drug-induced hallucinations, sparked off by the analogy between the simple geometric patterns seen in the early stages of hallucination, and similar patterns seen in fluid convection [36]. The initial concept of two histamine receptors, which provoked work leading to the discovery of the highly important H2 receptor antagonist drugs, was sparked by analogies with other substances acting at two sites with different effects [38]. Many other examples may be given.…”
Section: Specific Aspectsmentioning
confidence: 99%