Crecimiento endobiliar de las metástasis de carcinoma colorrectal☆

Gordo, Sandra Lopez; Ramos, Emilio; Torra, J. Torras; Garriga, Laura Lladó; Renau, Antoni Rafecas

doi:10.1016/j.ciresp.2015.02.008

Cited by 2 publications

(11 citation statements)

References 10 publications

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“…Certain authors propose anatomical surgery for these lesions, since it obtains a tumor‐free margin in the bile duct and because certain cases have the preoperative diagnosis of intrahepatic cholangiocarcinoma in which anatomical surgery is usually performed . More economical surgical approaches increase the risk of recurrence due to the existence of an R1 margin in the bile duct . Peungjesada et al.…”

Section: Discussionmentioning

confidence: 99%

“…The incidence of bile duct involvement due to liver metastases and/or macroscopic intraductal growth has not been definitively established, and ranges between 3.6% and 42% depending on the series [5,10,12,15,17,[20][21][22]. This incidence is striking in a rare condition [31].…”

Section: Discussionmentioning

confidence: 99%

“…Estrella et al [17] note that this rate is lower (3.6%) in retrospective than in prospective studies (10.6%) [2,17]. This large percentage difference is due to the fact that the studies do not distinguish between a small degree of biliary invasion due to liver metastasis, which is relatively frequent, microscopic involvement, and a true macroscopic intrabiliary extension, which is rare [20,22]. Estrella et al [17] state that 75% of macroscopic lesions produce major duct involvement and only 25% produce minor duct involvement; obviously, the ones that produce major duct involvement cause greater symptomatology and higher levels of radiological evidence [17,30].…”

Section: Discussionmentioning

confidence: 99%

“…Certain authors propose anatomical surgery for these lesions, since it obtains a tumor-free margin in the bile duct and because certain cases have the preoperative diagnosis of intrahepatic cholangiocarcinoma in which anatomical surgery is usually performed [2,16,21]. More economical surgical approaches increase the risk of recurrence due to the existence of an R1 margin in the bile duct [5,22,31]. Peungjesada et al [32] affirm that the hallmark and risk of bile duct involvement by colorectal liver metastasis is that the tumors can grow longitudinally, extending beyond the confines of the main parenchymal neoplastic mass.…”

Section: Discussionmentioning

confidence: 99%

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Intrabiliary metastases in colorectal cancer: a systematic review

Fragua

Vázquez

Figueira

et al. 2019

J Hepato Biliary Pancreat

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Background Liver metastases emerge during the course of colorectal cancer (CRC) in 25–50% of patients. A small proportion of patients present intrabiliary growth. The absence of large series means that little is known about intrabiliary metastasis (IBM), its radiological diagnosis, the most suitable surgical techniques, and its prognostic implications. Methods A systematic search without limits was performed. The studies selected included patients with a diagnosis of CRC and associated IBM, either synchronous or metachronous. Results Of 40 studies selected, 30 were case reports and 10 case series. The median time between diagnosis and IBM was 46.7 months (range 0–180). Most CRC metastases are CK7−/CK20+. Surgical treatment performed ranged from endoscopic resection to major hepatic resections combined with pancreatectomies. It seems that patients with IBM have a better survival than patients without this metastasis. Conclusion In a patient with a history of CRC presenting dilatation of the bile duct, IBM should be considered. More studies are needed to determine the most appropriate type of liver resection. It is also necessary to standardize the definition and terminology of this pathology, since the existing definitions may cause confusion and make it difficult to carry out case studies and case series.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Intrabiliary metastases in colorectal cancer: a systematic review

Fragua

Vázquez

Figueira

et al. 2019

J Hepato Biliary Pancreat

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“…Approximately 93% of all intrabiliary metastases have been shown to be of colorectal origin, with lung and kidney accounting for the majority of the remainder [ 1 , 2 ]. In all, 50% of intrabiliary colorectal metastases are found in major bile ducts [ 2 , 3 ]. Intrabiliary colorectal metastases are generally identified within 28 months of resection of the primary tumour [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Intrabilary obstruction by colorectal metastases

Traeger

Kiroff

2018

Journal of Surgical Case Reports

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Intrabiliary colorectal metastases are rare. We present a case of an 84-year-old man who developed obstructive jaundice secondary to intrabiliary growth of colorectal metastases. The patient presented with three weeks of jaundice and significant weight loss in the preceding months. The patient’s background included metastatic colorectal carcinoma, with a previous right hemicolectomy and left hepatectomy for liver metastases. A MRCP showed an obstruction of the biliary tract transitioning at the ampulla. Histology confirmed a malignant adenocarcinoma. When compared to the patient’s previous resected colorectal liver metastases, morphology and immunohistochemistry was consistent with colorectal metastases. This case highlights the importance of differentiating a new intraductal papillary neoplasm from a colorectal metastasis. Correctly identifying these lesions requires the use of MRCP and ERCP, as well as immunohistochemistry. This is a priority for clinicians to ensure appropriate therapy.

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Crecimiento endobiliar de las metástasis de carcinoma colorrectal☆

Cited by 2 publications

References 10 publications

Intrabiliary metastases in colorectal cancer: a systematic review

Intrabiliary metastases in colorectal cancer: a systematic review

Intrabilary obstruction by colorectal metastases

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