This work evaluated the development of colored cotton submitted to irrigation water of different salinity levels and organic matter doses from tanned manure. The experimental design was completely randomized in a 4 x 4 factorial scheme with 3 replications, totaling 48 experimental plots. The factors studied were 4 doses of organic matter (1, 4, 7 and 10%) and four levels of irrigation water salinity (0.26; 1, 2 and 4 dS m-1). The variables analyzed were plant height, stem diameter, number of leaves, number of fruits and fresh shoot mass. Significant effect of organic matter was observed on all studied variables, with a positive response on the increase of all variables as a function of increasing doses of organic matter. The isolated effect of salinity was significant for all parameters evaluated, except for the number of leaves, with significant reductions of 6.03; 3.27; 5.23; 6.94% in the parameters: plant height, stem diameter, number of fruits and shoot fresh weight respectively, for each unit increase of irrigation water salinity. The interaction between the variation sources studied had a significant effect only for fresh shoot mass, where the highest average for this parameter was observed at 10% organic matter dosage at irrigation water salinity level of 1.0 dS m-1.