Creutzfeldt-Jakob Disease

Abstract

Creutzfeldt-Jakob disease is the most common human prion pathology. We describe is emblematic of this disease in its form of onset and progression. We have reported the symptoms and the diagnostic possibilities: a 82 years old man accused suddenly confusion, agitation, memory impairment with rapid progression of cognitive decline and psychiatric signs and the appearance of other neurological deficits that led the patient quickly to coma leading to death. The pathological examination clarified the nature of patient's medical and it allowed players to make the diagnosis.