Crimean-Congo Haemorrhagic Fever: Treatment and Use of Ribavirin

Ergönül, Önder

doi:10.5152/kd.2016.02

Cited by 7 publications

(2 citation statements)

References 42 publications

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“…In our study, the physical examination findings included fevers, headaches, weakness, and diffuse muscular and articular pain. Thrombocytopenia (95.8%) and leukopenia (87.5%) were the most common laboratory findings, consistent with the literature [11,17,21]. All the patients included in our study recovered, and no mortality occurred following discharge.…”

Section: Discussionsupporting

confidence: 90%

Evaluation of Portal Vein Doppler Findings in Patients with Crimean–Congo Hemorrhagic Fever

Karavaş

Karakeçili

2019

Medicina

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Background and objectives: In this study, we compare portal vein Doppler ultrasound (US) findings between patients with Crimean–Congo hemorrhagic fever (CCHF) and healthy persons and investigate the practicability of these findings in the prediction of disease severity. Materials and Methods: In this prospective study, portal vein Doppler US was performed in patients diagnosed with CCHF and healthy persons between March 2016 and May 2018. The patients were grouped according to mild-to-moderate and severe progression of CCHF. Liver size, portal vein diameter, portal vein flow rate, spleen volume, and splenic vein diameter were recorded in the patients and healthy controls. Results: Of the 48 patients diagnosed with CCHF, 25 were male. According to the scoring made, 38 patients were evaluated as having mild-to-moderate disease progression, and 10 were evaluated as having severe disease progression. With respect to the Doppler US findings, liver size, spleen volume, portal vein diameter, splenic vein diameter, and portal vein flow rate were significantly higher in the patient group compared with the controls. However, no significant difference was found in these parameters between the severe and mild-to-moderate progression groups. Conclusions: In the evaluation of and follow-up with patients with CCHF, portal vein Doppler US is a non-invasive and reliable tool for diagnosis.

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Section: Discussionsupporting

confidence: 90%

Evaluation of Portal Vein Doppler Findings in Patients with Crimean–Congo Hemorrhagic Fever

Karavaş

Karakeçili

2019

Medicina

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“…However, field studies conducted in Turkey since 2005 have shown that the main tick species responsible for CCHF epidemics was Hyalomma marginatum. The CCHF virus has the most common geographic distribution among tick-borne viruses [1,[4][5][6].…”

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confidence: 99%

Evaluation of seroprevalence and clinical and laboratory findings of patients admitted to health institutions in Gümüşhane with suspicion of Crimean-Congo hemorrhagic fever

et al. 2021

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IntroductionCrimean-Congo hemorrhagic fever (CCHF) is a severe and fatal disease that is transmitted by ticks and often presents with bleeding symptoms in humans. The causative agent is the CCHF virus, an RNA virus of the Nairovirus lineage belonging to the family Bünyaviridae. It was first described in the Crimea in 1944, when it affected more than 200 people [1]. CCHF has been reported in more than 30 countries in Eastern Europe, Africa, the Balkans, Russia, Central Asian Republic, and the Middle East. The spread of the virus over a wide geographic area would result in a severe disease leading to high mortality in humans. The absence of a specific effective treatment and vaccine against the virus, in addition to its potential to be used as a bioterror agent or biological weapon, have made it an important human pathogen and a major public health problem worldwide [2]. In Turkey, CCHF is mainly seen in Erzurum,

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Evaluation of choroidal thickness and choroidal vascularity index in patients with Crimean-Congo hemorrhagic fever

Konuk¹,

Kılıç²,

Türkoğlu³

et al. 2023

Int Ophthalmol

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Purpose: To compare the choroidal thickness parameters of patients with Crimean-Congo Hemorrhagic Fever (CCHF) and healthy subjects using spectral domain optical coherence tomography (SD-OCT).Methods: In this study, right eye of 27 cases diagnosed with CCHF and 27 healthy subjects were evaluated. CCHF cases were evaluated after history of tick bite and hospitalization. Choroidal thickness was measured using EDI-OCT. Choroidal thickness was measured at ve different points at the subfovea, temporal and nasal quadrants at 1000 μm intervals up to 2000 μm from the fovea. Choroidal vascular index (CVI) was de ned as the ratio of luminal area (LA) to total choroidal area (TCA), including the total and 1500 μm center of the macula (CVI total and CVI 1500 ).Result: Choroidal thickness in CCHF group was measured thicker in each quadrant than in the control group and the thickness in the subfoveal and nasal quadrants was signi cantly greater. TCA, stromal area (SA), LA were found to be signi cantly higher, but no signi cant difference was found between CVI and CVI 1500 . Conclusion: Our ndings suggest that the choroidal structure may be affected by CCHF disease.

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Crimean-Congo Haemorrhagic Fever: Treatment and Use of Ribavirin

Abstract: Crimean-Congo haemorrhagic fever

Cited by 7 publications

References 42 publications

Evaluation of Portal Vein Doppler Findings in Patients with Crimean–Congo Hemorrhagic Fever

Evaluation of Portal Vein Doppler Findings in Patients with Crimean–Congo Hemorrhagic Fever

Evaluation of seroprevalence and clinical and laboratory findings of patients admitted to health institutions in Gümüşhane with suspicion of Crimean-Congo hemorrhagic fever

Evaluation of choroidal thickness and choroidal vascularity index in patients with Crimean-Congo hemorrhagic fever

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