Crimean-Congo Hemorrhagic Fever and Hypertention: A Case Report

Metanat, Maliheh; Sharifi-Mood, Batool; Alavi-Naini, Roya; Kermansaravi, Fatihe; Hamzehnezhad, Majid

doi:10.5812/archcid.20696

Cited by 4 publications

(5 citation statements)

References 11 publications

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“…In addition, it was also shown that metabolic demand is increased in neurons and bloodbrain barrier was disrupted with acidosis and higher amounts of excitatory amino acids in patients infected by CCHF. Studies showed that IL-10 release results in delayed and attenuated immune response, which, in turn, causes uncontrolled release of TNF-α, IFN-γ and cytokines, resulting in promotion of intrinsic pathway of intravascular coagulation [7,8].…”

Section: Discussionmentioning

confidence: 99%

Association of Ischemic Brainstem Stroke Following Tick Bite and Crimean-Congo Hemorrhagic Fever: A Rare Presentation

Ulusoy¹

2017

J Clin Res Bioeth

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Purpose: Crimean-Congo hemorrhagic fever (CCHF) is a viral zoonosis that may be associated with high mortality rate. Several inflammatory mediators (interleukins, IFN-γ, TNF-α etc.) released during disease have been implied in the pathogenesis, which also cause ischemia.Case report: A 60-years old man working in livestock production presented to emergency department with vomiting, fever and impaired balance and gait. In laboratory evaluation, it was found that there was elevation in hepatic enzymes, decreased platelet and leukocyte counts. The patient underwent magnetic resonance (MR) imaging due to gait disorder, revealing restricted diffusion at pons compatible with acute infarct. The patient was admitted with the diagnosis of CCHF and ischemic stroke secondary to infection. During follow-up, no hemorrhage was observed and the patient was discharged as he achieved clinical recovery. Conclusion:In this case report, we discussed ischemic stroke developed secondary to infection in a patient with CCHF and its management in the light of literature.

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Section: Discussionmentioning

confidence: 99%

Association of Ischemic Brainstem Stroke Following Tick Bite and Crimean-Congo Hemorrhagic Fever: A Rare Presentation

Ulusoy¹

2017

J Clin Res Bioeth

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“…Hematological findings may change from thrombocytopenia and petechial rash to massive bleedings. Several complications like visceral bleedings, infections, compartment syndrome and even hypertension may accompany the disease (6)(7)(8). We had a CCHF case complicated with pararenal abscess, which had not been reported as a complication of CCHF before.…”

Section: Introductionmentioning

confidence: 96%

A Case of Crimean Congo Hemorrhagic Fever Complicated With Pararenal Abscess

Sari¹,

Temoçin

Demirelli

et al. 2015

Arch Clin Infect Dis

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Introduction: Crimean-congo hemorrhagic fever (CCHF) is a tick-borne zoonotic disease caused by Nairovirus of the Bunyaviridae family. It affects multiple systems and case fatality rate may vary between 5% -30%. It also causes several complications. Here we presented a pararenal abscess case complicating CCHF, never reported before. Case Presentation: A 49-year-old male dealing with livestock husbandry was admitted to Ankara Training and Research Hospital with three days of complaints including fever, malaise, headache, myalgia, nausea, vomiting, diarrhoea and hematuria. Laboratory findings (thrombocytopenia and elevated alanine transaminase (ALT) and aspartate transaminase (AST)) were suggesting CCHF and he was hospitalized. The diagnosis was confirmed by CCHF reverse transcriptase-polymerase chain reaction (RT-PCR) and IgM positivity. Although his clinical condition was improving, he developed right flank pain on the fourth day. The computerized tomography showed abscess (pararenal 44 mm × 17 mm). With appropriate antibiotherapy and percutaneous drainage, his clinical and laboratory findings regressed. Conclusions: Unexpected complications may be seen during the course of CCHF. Patients must be closely followed up.

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“…Many reports have been shown that contact with infected animal tissue and blood have transmitted the virus to humans. Also, consumption of uncooked meat can also transmit the infection to humans (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15). Five years ago, we reported 4 patients with CrimeanCongo hemorrhagic fever, who acquired the illness following consumption of uncooked sheep liver (2).…”

Section: U N C O R R E C T E D P R O O Fmentioning

confidence: 99%

“…CCHF can also transmit from the infected person to another person through contact with infectious body fluids, such as infected blood (1,(4)(5)(6)(7)(8). Transmission of CCHFV has been reported in hospitals because of improper sterilization of medical equipment, through needle sticks, and air among patients who have been hospitalized in the same wards.…”

Section: Introductionmentioning

confidence: 99%

Report of a Family with Crimean-Congo Hemorrhagic Fever Following Contact with Frozen Meat: A Case Seires Study

Metanat¹,

Sharifi-Mood²,

Fathollahzadeh³

et al. 2017

Arch Clin Infect Dis

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Introduction: Crimean-Congo hemorrhagic fever (CCHF) is caused by a tick-borne virus in the family of Bunyaviridae. A hard tick, in the genus of Hyalomma, is a reservoir and also a vector for CCHF virus. Infection in humans usually occurs by infected tick bite or through contact with infected animal tissues and blood. CCHF can also transmit from one infected person to another through contact with infectious blood or body fluids. Human-to human transmission is also reported as a nosocomial infection. Case Presentation: Here, we presented 5 patients from a family with Crimean-Congo hemorrhagic fever, who got the illness at the same time when they cut the frozen meat together. Fortunately, all patients referred to hospital soon and received treatment during 24 to 72 hours after the first sign or symptom was presented. Conclusions: Frozen meat can transmit CCHFV to humans, which can be due to high viral load or a virus with high virulence in the infected animal tissues.

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Crimean-Congo Hemorrhagic Fever and Hypertention: A Case Report

Cited by 4 publications

References 11 publications

Association of Ischemic Brainstem Stroke Following Tick Bite and Crimean-Congo Hemorrhagic Fever: A Rare Presentation

Association of Ischemic Brainstem Stroke Following Tick Bite and Crimean-Congo Hemorrhagic Fever: A Rare Presentation

A Case of Crimean Congo Hemorrhagic Fever Complicated With Pararenal Abscess

Report of a Family with Crimean-Congo Hemorrhagic Fever Following Contact with Frozen Meat: A Case Seires Study

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