Pulmonary infections and neoplasms are the most common chest manifestations in patients infected with the human immunodeficiency virus. A case of a young patient with a history of being a smoker and drug addict is presented, who presented with a wet cough, yellowish sputum, hemoptysis, easy fatigue, loss of appetite and weight loss, who was referred with a possible diagnosis of tuberculosis but after admission. he was diagnosed with HIV and advanced lung cancer. The diagnosis was made by fine needle puncture after which he presented a hemothorax as a complication, which caused his death.