Introduction: Neoplasms of the central nervous system are epidemiologically very important, as they are the second most common type of tumors in childhood and adolescence 3 . Objective: Central nervous system tumors can present very varied clinical manifestations, depending mainly on the child's age and location 8 . There is a spectrum of syndromes associated with these tumors, which this article aims to describe. Method: The search was carried out in the PubMed, BVS and Scielo databases, and was limited to articles between the period 2019 to 2023 that met the criteria of being literature reviews and case reports. Result: Based on the findings, the most common syndromes in children with central nervous system tumors, depending on their location and extent, are the intracranial, ataxic, pyramidal, convulsive, neuroendocrine, diencephalic and macrocranial hypertension syndromes.