CRISPR/Cas9-mediated generation of auxotrophic Edwardsiella piscicida mutants and immunization in olive flounder (Paralichthys olivaceus)

Lee, Eun Gyeong; Kwak, Jun Soung; Kim, Ki Hong

doi:10.1016/j.fsi.2022.01.040

Fish & Shellfish Immunology

2022

DOI: 10.1016/j.fsi.2022.01.040

|View full text |Cite

CRISPR/Cas9-mediated generation of auxotrophic Edwardsiella piscicida mutants and immunization in olive flounder (Paralichthys olivaceus)

Eun Gyeong Lee

Jun Soung Kwak

Ki Hong Kim

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

The rise of the opportunists: What are the drivers of the increase in infectious diseases caused by environmental and commensal bacteria?

Samsing,

Barnes

2024

Reviews in Aquaculture

View full text Add to dashboard Cite

The aquaculture sector is currently experiencing a global disease crisis. Emerging bacterial diseases—often opportunistic or syndromic—have collapsed production in nations across the world. Losses in the shrimp industry associated with opportunistic Vibrio spp. exceed 40% of global capacity. This paper reviews potential drivers of syndromic diseases involving opportunistic bacterial pathogens affecting global aquaculture. We provide key examples from major industries where such conditions have prompted greater antibiotic use and have resulted in significant mortality. We challenge the conventional definitions of opportunistic pathogens and propose a fluid categorisation that acknowledges the continuum of host adaptation and the complexity of microbial ecology. We discuss the implications of environmental and dietary stressors such as climate change, coastal eutrophication and pollution, and the transition to plant‐based feeds, which have been linked to impaired epithelial barrier function, gut health disorders and increased disease susceptibility. We critique the ‘one‐pathogen one‐disease’ paradigm, suggesting that Rothman's causal pie model is more useful for understanding opportunistic infections as it emphasises the multicausal nature of disease. We provide examples of bacterial and viral interactions in aquatic disease and occurrence of bacterial diseases resulting from host damage from eukaryotic parasites or increasing frequency and severity of interventions to control such parasites. We recognise the need for corroborative evidence to validate the rise of opportunistic bacterial pathogens as a global trend, and we advocate for the application of nuanced disease causation models to reduce the incidence of opportunistic infections and improve the sustainability of the aquaculture industry.

show abstract

The rise of the opportunists: What are the drivers of the increase in infectious diseases caused by environmental and commensal bacteria?

Samsing,

Barnes

2024

Reviews in Aquaculture

View full text Add to dashboard Cite

show abstract

CRISPR/Cas Technology in Disease Prevention and Control of Aquatic Animals

Lin,

Zhang,

Wang

et al. 2024

Reviews in Aquaculture

View full text Add to dashboard Cite

The CRISPR/Cas genome editing technology, with its advantages of simplicity, high efficiency, and cost‐effectiveness, has become a key tool for dissecting gene function, knocking out harmful/undesirable genes, and repairing defective genes. It has also shown great potential in the genome editing of aquatic animals such as tilapia, carp, salmon, and sea urchins. Disease prevention and control are core areas of aquatic animal research and the aquaculture industry. Novel technologies based on CRISPR/Cas, such as rapid diagnostic kits for aquatic diseases and species‐specific drugs against parasites, have been developed in the disease diagnosis, treatment, and prevention of aquatic animals. Based on our work in these fields, this review summarizes the relevant new technologies and latest progress, aiming to provide readers with a quick and comprehensive understanding of the application status and future trends of CRISPR/Cas technology in the prevention and control of aquatic diseases and to provide a reference for related fields.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

CRISPR/Cas9-mediated generation of auxotrophic Edwardsiella piscicida mutants and immunization in olive flounder (Paralichthys olivaceus)

Cited by 2 publications

References 33 publications

The rise of the opportunists: What are the drivers of the increase in infectious diseases caused by environmental and commensal bacteria?

The rise of the opportunists: What are the drivers of the increase in infectious diseases caused by environmental and commensal bacteria?

CRISPR/Cas Technology in Disease Prevention and Control of Aquatic Animals

Contact Info

Product

Resources

About