2023
DOI: 10.1002/jmv.29090
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CRISPR dual enzyme cleavage triggers DNA and RNA substrate cleavage for SARS‐CoV‐2 dual gene detection

Tong Jiang,
Runde Liu,
Jilu Shen

Abstract: The widespread dissemination of coronavirus 2019 imposes a significant burden on society. Therefore, rapid detection facilitates the reduction of transmission risk. In this study, we proposed a multiplex diagnostic platform for the rapid, ultrasensitive, visual, and simultaneous detection of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) open reading frame 1ab (ORF1ab) and N genes. A visual diagnostic method was developed using a clustered regularly interspaced short palindromic repeat (CRISP… Show more

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Cited by 5 publications
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