CRISPR in agriculture and it’s ethical implications: A bibliometric analysis

Kolkur, Sagar U.; Sharma, Akriti; Gouda, M.N. Rudra; Praveen, K.V.; Singh, Alka

doi:10.1016/j.foohum.2024.100322

Food and Humanity

2024

DOI: 10.1016/j.foohum.2024.100322

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CRISPR in agriculture and it’s ethical implications: A bibliometric analysis

Sagar U. Kolkur,

Akriti Sharma,

M.N. Rudra Gouda

et al.

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2024

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Cited by 1 publication

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Mitigating Antibiotic Resistance: The Utilization of CRISPR Technology in Detection

Zhang,

Huang,

Zhang

et al. 2024

Biosensors

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Antibiotics, celebrated as some of the most significant pharmaceutical breakthroughs in medical history, are capable of eliminating or inhibiting bacterial growth, offering a primary defense against a wide array of bacterial infections. However, the rise in antimicrobial resistance (AMR), driven by the widespread use of antibiotics, has evolved into a widespread and ominous threat to global public health. Thus, the creation of efficient methods for detecting resistance genes and antibiotics is imperative for ensuring food safety and safeguarding human health. The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) systems, initially recognized as an adaptive immune defense mechanism in bacteria and archaea, have unveiled their profound potential in sensor detection, transcending their notable gene-editing applications. CRISPR/Cas technology employs Cas enzymes and guides RNA to selectively target and cleave specific DNA or RNA sequences. This review offers an extensive examination of CRISPR/Cas systems, highlighting their unique attributes and applications in antibiotic detection. It outlines the current utilization and progress of the CRISPR/Cas toolkit for identifying both nucleic acid (resistance genes) and non-nucleic acid (antibiotic micromolecules) targets within the field of antibiotic detection. In addition, it examines the current challenges, such as sensitivity and specificity, and future opportunities, including the development of point-of-care diagnostics, providing strategic insights to facilitate the curbing and oversight of antibiotic-resistance proliferation.

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Mitigating Antibiotic Resistance: The Utilization of CRISPR Technology in Detection

Zhang,

Huang,

Zhang

et al. 2024

Biosensors

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show abstract

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CRISPR in agriculture and it’s ethical implications: A bibliometric analysis

Cited by 1 publication

References 17 publications

Mitigating Antibiotic Resistance: The Utilization of CRISPR Technology in Detection

Mitigating Antibiotic Resistance: The Utilization of CRISPR Technology in Detection

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