Criss-cross Cycloadditions on Ketazines Derived from Alicyclic Ketones

Abstract

Abstract:The reactivity of alicyclic ketazines in criss-cross cycloadditions was investigated. They react with potassium cyanate and ammonium thiocyanate in the presence of acetic acid to form spirocyclic perhydro [1,2,4]

Selective Reduction of Azines to Benzyl Hydrazones with Sodium Borohydride Catalyzed by Mesoporous Silica‐Supported Silver Nanoparticles: A Catalytic Route towards Pyrazole Synthesis

“…[3][4][5][6] Their basic synthesisi ncludes the reactiono ft wo molecules of identical carbonyl compounds( symmetrical azines) or two different carbonylc ompounds( unsymmetrical azines) with hydrazine. [10,11] Furthermore,a ldazines as conjugated dienes have been applied in [1,3]-cycload-ditionsw ith electron-deficient unsaturated molecules to afford 1,5-diazabicyclo [3.3.0]octanes via the socalled criss-cross reaction. [10,11] Furthermore,a ldazines as conjugated dienes have been applied in [1,3]-cycload-ditionsw ith electron-deficient unsaturated molecules to afford 1,5-diazabicyclo [3.3.0]octanes via the socalled criss-cross reaction.…”

“…Their basic synthesis includes the reaction of two molecules of identical carbonyl compounds (symmetrical azines) or two different carbonyl compounds (unsymmetrical azines) with hydrazine . Recently, they have attracted interest as precursors for the synthesis of 1,4‐dihydropyridines, 1,3,4‐oxadiazoles, pyrazoles and various heterocycles ,. Furthermore, aldazines as conjugated dienes have been applied in [1,3]‐cycloadditions with electron‐deficient unsaturated molecules to afford 1,5‐diazabicyclo[3.3.0]octanes via the so‐called criss‐cross reaction…”

New Synthesis of Perhydrotriazolotriazoles Catalyzed by TiCl4under Ambient Conditions

“…Main recent papers describing synthesis of perhydrotriazolotriazoles by classical method, 19,20 but this method has defects such as long reaction times and low yield. Herein we report a facial and efficient method for the synthesis perhydrotriazolotriazoles catalyzed by TiCl 4 .…”

Copper-catalyzed decarboxylative C−P cross coupling of arylpropiolic acids with dialkyl hydrazinylphosphonates leading to alkynylphosphonates

“…In contrast, dialkyl hydrazinylphosphonates is more stable and easily available, which can be conveniently prepared according to the known literature. [23] Therefore, using dialkyl hydrazinylphosphonates instead of H-phosphonates might make the coupling reaction easier to operate. In this context, we attempt to develop a mild, simple, and green protocol for the copper-mediated oxidative decarboxylative coupling of arylpropiolic acids with dialkyl hydrazinyl phosphonates.…”