Criteria for Pulmonary and Respiratory Failure in COPD Patients – A Theoretical Study Based on Clinical Data

Kawakami, Yoshikazu; Irie, Tadashi; Kishi, Fujiya

doi:10.1159/000194515

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…Diagnostic criteria for respiratory insuffi ciency include Pa O 2 of 60 mmHg or less. Below this value, mixed venous oxygen pressure (Pv O 2 ), which refl ects systemic oxygen supply and demand, is below the normal limits of 35 mmHg [49]. COPD staging is an important prognostic factor [50][51][52], and prognosis is poor if respiratory insuffi ciency is present [53,54] (Fig.…”

Section: Preoperative Evaluationmentioning

confidence: 99%

Guideline-oriented perioperative management of patients with bronchial asthma and chronic obstructive pulmonary disease

2008

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Increased airway hyperresponsiveness is a major concern in the perioperative management of patients with bronchial asthma and chronic obstructive pulmonary disease. Guidelines using evidence-based medicine are continually being updated and published regarding the diagnosis, treatment, and prevention of these respiratory disorders. Perioperative management in these patients involves: (1) adequate control of airway hyperresponsiveness, including detection of purulent sputum and infection before surgery; (2) evidence-based control of anesthesia; and (3) the aggressive use of beta-2 adrenergic stimulants and the systemic administration of steroids for the treatment of acute attacks. Good preoperative control, including the use of leukotriene antagonists, can reduce the incidence of life-threatening perioperative complications. Awareness of recent guidelines is thus important in the management of patients with airway hyperresponsiveness. This review covers the most recent guidelines for the perioperative management of patients with bronchial asthma and chronic obstructive pulmonary disease.

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Section: Preoperative Evaluationmentioning

confidence: 99%

Guideline-oriented perioperative management of patients with bronchial asthma and chronic obstructive pulmonary disease

2008

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“…Additionally, type I failure is defined as arterial carbon dioxide tension (PaCO2) of below 45 mmHgand type II failure, PaCO2over 45 mmHg. Several reports on patients with chronic respiratory failure (mostly due to COPD) suggest that a PaO2of60 mmHg is a critical level of deteriorated pulmonary as well as circulatory abnormalities (2). This level also seems to be critical for oxygen supply to the peripheral tissue as evaluated by survival in COPD(3).…”

Section: Current Criteria Of Chronic Respiratory Failurementioning

confidence: 99%

Current Status and Research on Chronic Respiratory Failure in Japan.

Kawakami

1996

Intern. Med.

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Quantification of nonuniform distribution of hemi-lung perfusion in chronic obstructive pulmonary disease

Mitomo¹

2015

Ann Nucl Med

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Nonuniform distribution (NUD) of perfusion on single photon emission computed tomography (SPECT) is caused by impaired perfusion-related fluctuations of the functional volume (FFV). It was determined if digital analysis of NUD in each hemi-lung damaged by chronic obstructive pulmonary disease (COPD) could improve the whole lung impairment assessment. We examined 665 subjects and 8 controls by SPECT. The basic whole lung SPECT volume was defined at 10% of maximum whole lung count cutoff threshold (T h). For the whole lung and each hemi-lung, the 10% T h width volume, FFV rate, and misfit from the control were calculated at every T h width number (n) from 1 to 9 for every additional 10% T h from 10 to 100%. The misfit value integrated from 1 to 9 of n was defined by 3 NUD indices: D, whole lung NUD index; D rl , the index for the sum of each hemi-lung NUD; and D (I) , the NUD index with every interpolating pattern in which FFV rates of hemi-lungs comprised negative and positive value at the same n. D rl index was the sum of D and D (I) indices in all patients. D rl and D indices significantly increased in pulmonary disease subjects relative to those of the normal group and non-pulmonary disease subjects. D rl and D indices increased in COPD subjects. Progressive COPD subjects had larger D rl index values and "diffuse and even" hemi-lung impairment. The three indices quantizing FFV itself leading to NUD helped to digitally evaluate the degree of lung impairment of perfusion. Clinically, it is expected that the NUD indices and images obtained by SPECT, which visually and digitally show the pathological fluctuations in perfusion caused by lung impairment, will be able to provide specific and useful information for improving treatment and/or care of subjects with COPD.

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Criteria for Pulmonary and Respiratory Failure in COPD Patients – A Theoretical Study Based on Clinical Data

Cited by 4 publications

References 6 publications

Guideline-oriented perioperative management of patients with bronchial asthma and chronic obstructive pulmonary disease

Guideline-oriented perioperative management of patients with bronchial asthma and chronic obstructive pulmonary disease

Current Status and Research on Chronic Respiratory Failure in Japan.

Quantification of nonuniform distribution of hemi-lung perfusion in chronic obstructive pulmonary disease

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