Criteria in the Prognostic of Generalization of Bacterioses in Dogs With Uterine Inflammation

Pimenov, N V; Лаптев, С. В.; Permyakova, K. Yu.; Ivannikova, Regina F.; Marzanova, S. N.

doi:10.52419/issn2072-2419.2022.3.11

Cited by 2 publications

(2 citation statements)

References 12 publications

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“…Leptospirosis belongs to the group of transmissible natural focal infections [1][2]. Every year tens of thousands of dogs are examined for leptospirosis.…”

Section: Introductionmentioning

confidence: 99%

“…Pathogens of the Canicola serogroup, which often cause leptospirosis in dogs [3], pose an epidemiological danger associated with constant human contact with the sources of the pathogen -dogs. At the same time, morphologically identical leptospira differ significantly in the features of epidemic and epizootological implementation [2,4]. Based on PCR, diagnostic test systems have been developed to identify the genomes of all known leptospira species [5].…”

Section: Introductionmentioning

confidence: 99%

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Prognosis of septic complications and the outcome of the disease according to the saps score scale in dogs with leptospirosis

Laptev,

Pimenov,

Marzanova

et al. 2023

BIO Web Conf.

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The article presents the results of the analysis of clinical and laboratory data of 24 dogs in order to create a convenient model for the formation of the prognosis of septic complications and the outcome of the disease. The use of the SAPS scale simplifies the assessment of physiological disorders caused by the clinical manifestation of SOURCE, MODS and CARS and allows you to make a reliable forecast of possible complications in dogs with leptospirosis. So, with complications, there is a slight decrease in the number of red blood cells and hemoglobin, a slight increase in ESR. The level of AST, ALT has been increased. An increase in the level of bilirubin, urea and creatinine was revealed. The level of rod-shaped neutrophils is increased, and segmented neutrophils are lowered. The prognosis of septic complications in dogs with leptospirosis on the SAPS scale allows us to assess the degree of danger of physiological disorders caused by the clinical manifestations of SIRS, MODS and CARS in the shortest possible time. should leave 8 mm of space above the abstract and 10 mm after the abstract. The heading Abstract should be typed in bold 9-point Arial. The body of the abstract should be typed in normal 9-point Times in a single paragraph, immediately following the heading. The text should be set to 1 line spacing.

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“…Leptospirosis belongs to the group of transmissible natural focal infections [1][2]. Every year tens of thousands of dogs are examined for leptospirosis.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prognosis of septic complications and the outcome of the disease according to the saps score scale in dogs with leptospirosis

Laptev,

Pimenov,

Marzanova

et al. 2023

BIO Web Conf.

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Heuristic approaches to risk assessment and prognosis of sepsis in dogs

Laptev,

Pimenov,

Mazanova

et al. 2023

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This study examines approaches to assessing the risk of death and predicting the development of sepsis in dogs. Sepsis remains one of the key clinical problems in medicine and veterinary medicine, due to its widespread prevalence throughout the world, leading to high mortality. Sepsis is based on the reaction of systemic inflammation of the body, which is realized in the presence of signs of SIRS, bacteremia and/or an infectious focus of various nature in combination with acute signs of organ dysfunction and/or evidence of microbial dissemination. Since sepsis develops only progressively, it is impossible for the animal to recover independently without providing it with timely and appropriate medical care. Today, one of the key issues remains improving approaches to assessing the risk of death and predicting the development of sepsis in dogs. An attempt to combine the pathogenicity factors of an infectious agent and the failure of the host’s defense mechanisms is reflected in the concepts of PIRO, SAPS and MODS, which evaluate the links in the etiopathogenesis of sepsis. Thus, heuristic approaches will allow us to come closer to the development of pathogenetically based methods for assessing the risk of death of animals and predicting the development of sepsis in dogs. These approaches are based on criteria for assessing PIRO indicators: predisposition (P), including breed, sex, age of the animal; infection (I) associated with the type of pathogen detected; systemic response of the body to infection R, characterized by the main clinical indicators - body temperature, heart rate, respiratory rate and the number of leukocytes in the blood; organ dysfunction (O) identified in one or more organs of the animal. An important role in the objective prognosis is given to the evaluation criteria on the SAPS scale, taking into account changes in indicators towards hyperinflammation (SIRS) or immunosuppression (MODS), which determine the stage of development of sepsis and the likelihood of the risk of death of the sick animal. On average, the predictive accuracy of quantifying disease severity systems is 70–85%. An algorithm for translating clinical and laboratory data into a SAPS scale of indicators (scores) that determines the severity of the disease in leptospirosis in dogs is proposed. It has been shown that on the SAPS scale for canine leptospirosis, a score of 29

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Criteria in the Prognostic of Generalization of Bacterioses in Dogs With Uterine Inflammation

Cited by 2 publications

References 12 publications

Prognosis of septic complications and the outcome of the disease according to the saps score scale in dogs with leptospirosis

Prognosis of septic complications and the outcome of the disease according to the saps score scale in dogs with leptospirosis

Heuristic approaches to risk assessment and prognosis of sepsis in dogs

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