Critical appraisal of the European Union Scientific Committee on Health, Environmental and Emerging Risks (SCHEER) <i>Preliminary Opinion on electronic cigarettes</i>

O’Leary, Renée; Polosa, Riccardo; Volti, Giovanni Li

doi:10.1101/2020.11.09.20228296

Cited by 2 publications

(1 citation statement)

References 67 publications

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“…First, there is a relatively limited number of human studies on the health effects of ENDS, contributing to the uncertainty on their clinical impact [27, 34, 35]. Second, decisions by clinicians and policy makers are often based on beliefs that are not supported by the available studies [36, see also 37 38]. Research evidence on the health risks of ENDS is a priority for decision-making because ENDS could represent an excellent tobacco harm reduction opportunity [34] if their long-term safety would be demonstrated.…”

Section: Methodsmentioning

confidence: 99%

Respiratory and Cardiovascular Health Effects of E-Cigarette Substitution: Protocol for Two Living Systematic Reviews

O’Leary

Qureshi

Rosa

et al. 2021

Preprint

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BackgroundDespite the clear risks of tobacco use, millions of people continue to smoke. Electronic nicotine delivery systems (ENDS), commonly called e-cigarettes, have been proposed as a substitute for those who are unwilling or unable to quit. Current systematic and narrative reviews on the health effects of ENDS use, respiratory and cardiovascular effects in particular, have come to differing conclusions.ObjectiveThe purpose of our two systematic reviews is to critically assess and synthesize the available human studies on the respiratory and cardiovascular health effects of ENDS substitution for people who smoke. The primary goal is to provide clinicians with evidence on the health effects of ENDS substitution to inform their treatment recommendations and plans. The twin goal is to promote the health literacy of ENDS users with facts on the health effects of ENDS. A secondary goal is to develop policy briefs to provide governmental bodies with a preliminary assessment of the potential public health impacts of ENDS.MethodsThese two reviews will be living systematic reviews. The systematic reviews will be initiated with a baseline review. Studies will be evaluated with the JBI quality assessment tools and a checklist of biases drawn from the Centre for Evidence Based Medicine’s Catalogue of Bias. A narrative synthesis is planned due to the heterogeneity of data. A search for recently published studies will be conducted every three months, and an updated review published every six months for the duration of the project or possibly longer.ResultsThe baseline and updated reviews will be published in a peer review journal. The review findings will be reported in a white paper for clinicians, a fact sheet for people who use ENDS, and country-specific policy briefs.ConclusionsThe substitution of ENDS for cigarettes is one of the ways to potentially reduce the risks of smoking. Clinicians and their patients need to understand the potential benefits and possible risks of substituting ENDS for cigarettes. Our living systematic reviews seek to highlight the best and most up-to-date evidence in this highly contentious and fast-moving field of research.

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Section: Methodsmentioning

confidence: 99%

Respiratory and Cardiovascular Health Effects of E-Cigarette Substitution: Protocol for Two Living Systematic Reviews

O’Leary

Qureshi

Rosa

et al. 2021

Preprint

Self Cite

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Effects of Providing Tailored Information About e-Cigarettes in a Web-Based Smoking Cessation Intervention: Protocol for a Randomized Controlled Trial (Preprint)

Elling¹,

Crutzen²,

Talhout³

et al. 2021

Preprint

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BACKGROUND There is an ongoing debate whether or not electronic cigarettes (e-cigarettes) should be advocated for smoking cessation. Because of this uncertainty, information about the use of e-cigarettes for smoking cessation is usually not provided in governmental smoking cessation communications. However, there is an information need among smokers, because – despite this uncertainty – e-cigarettes are used by many smokers to reduce and/or quit tobacco smoking. OBJECTIVE To describe the study protocol of a Randomized Controlled Trial (RCT) to assess the effect of providing tailored information about e-cigarettes compared to not providing this information on determinants of decision-making and smoking reduction and abstinence. This information is provided in the context of a digital smoking cessation intervention. METHODS An RCT with a 6-month follow-up period will be conducted among adult smokers motivated to quit smoking within 5 years. Participants will be 1:1 randomized into either the intervention condition or control condition. Grounded on the I-Change Model, participants in both conditions will receive tailored feedback on attitude, social influence, preparatory plans, self-efficacy, and coping plans. Information on six clusters of smoking cessation methods will be provided in both conditions. Smokers in the intervention condition will also receive detailed tailored information on e-cigarettes; smokers in the control condition will not receive this information. The primary outcome measure will be the number of tobacco cigarettes smoked in the past 7 days. Secondary outcome measures will include 7-day point prevalence tobacco abstinence, 7-day point prevalence e-cigarette abstinence, and determinants of decision-making (i.e., knowledge and attitude regarding e-cigarettes). All outcomes will be self-assessed through web-based questionnaires. RESULTS Recruitment began in March 2020 and was completed by July 2020. We expect to publish the results in March 2021. CONCLUSIONS The experimental design of the study allows conclusions to be formed regarding the effects of tailored information about e-cigarettes on decision-making and smoking behavior. The findings can inform the development of future smoking cessation interventions. CLINICALTRIAL Dutch Trial Register, Trial NL8330 (https://www.trialregister.nl/trial/8330)

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Critical appraisal of the European Union Scientific Committee on Health, Environmental and Emerging Risks (SCHEER) Preliminary Opinion on electronic cigarettes

Cited by 2 publications

References 67 publications

Respiratory and Cardiovascular Health Effects of E-Cigarette Substitution: Protocol for Two Living Systematic Reviews

Respiratory and Cardiovascular Health Effects of E-Cigarette Substitution: Protocol for Two Living Systematic Reviews

Effects of Providing Tailored Information About e-Cigarettes in a Web-Based Smoking Cessation Intervention: Protocol for a Randomized Controlled Trial (Preprint)

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