Critical aspects of Raman spectroscopy as a tool for postmortem interval estimation

Falgayrac, Guillaume; Vitale, Raffaele; Delannoy, Yann; Behal, Hélène; Penel, Guillaume; Duponchel, Ludovic; Colard, Thomas

doi:10.1016/j.talanta.2022.123589

Cited by 8 publications

(5 citation statements)

References 42 publications

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“…Another potential approach for characterizing bone components at the molecular level is Raman spectroscopy [ 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 ]. Through the emission of electromagnetic radiation, it can detect the presence of collagen and mineral phases that constitute the extracellular matrix [ 57 , 58 , 59 ].…”

Section: Resultsmentioning

confidence: 99%

Estimation of Late Postmortem Interval: Where Do We Stand? A Literature Review

Franceschetti

Amadasi

Bugelli³

et al. 2023

Biology

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Estimating time since death can be challenging for forensic experts, and is one of the most challenging activities concerning the forensic world. Various methods have been assessed to calculate the postmortem interval on dead bodies in different stages of decomposition and are currently widely used. Nowadays, the only well-recognized dating technique is carbon-14 radioisotope measurement, whereas other methods have been tested throughout the years involving different disciplines with different and sometimes not univocal results. Today, there is no precise and secure method to precisely determine time since death, and late postmortem interval estimation remains one of the most debated topics in forensic pathology. Many proposed methods have shown promising results, and it is desirable that with further studies some of them might become acknowledged techniques to resolve such a difficult and important challenge. The present review aims at presenting studies about the different techniques that have been tested in order to find a valuable method for estimating time since death for skeletal remains. By providing a comprehensive overview, the purpose of this work is to offer readers new perspectives on postmortem interval estimation and to improve current practice in the management of skeletal remains and decomposed bodies.

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Section: Resultsmentioning

confidence: 99%

Estimation of Late Postmortem Interval: Where Do We Stand? A Literature Review

Franceschetti

Amadasi

Bugelli³

et al. 2023

Biology

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“…Over the past years, multiple studies have been conducted to explore the use of vibrational spectroscopy in analyzing bones for forensic purposes [112]. These studies have examined various questions, such as comparing analytical techniques [35,113] and chemometric methods [47], estimating the PMI [28,114], and differentiating between archaeological and forensic bones [105,115].…”

Section: Discussionmentioning

confidence: 99%

Raman spectroscopy for postmortem interval estimation of human skeletal remains: A scoping review

Woess

Huck

Badzoka

et al. 2023

Journal of Biophotonics

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Estimating postmortem intervals (PMI) is crucial in forensic investigations, providing insights into criminal cases and determining the time of death. PMI estimation relies on expert experience and a combination of thanatological data and environmental factors but is prone to errors. The lack of reliable methods for assessing PMI in bones and soft tissues necessitates a better understanding of bone decomposition. Several research groups have shown promise in PMI estimation in skeletal remains but lack valid data for forensic cases. Current methods are costly, time‐consuming, and unreliable for PMIs over 5 years. Raman spectroscopy (RS) can potentially estimate PMI by studying chemical modifications in bones and teeth correlated with burial time. This review summarizes RS applications, highlighting its potential as an innovative, nondestructive, and fast technique for PMI estimation in forensic medicine.

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“…14,15 Moreover, Raman spectroscopy has gained increasing attention within the forensic eld, such as for identifying illegal drugs, 16 examining questioned documents, 17,18 detecting gunshot residue, 19 analyzing body uid trace evidence acquired from crime scenes, [19][20][21] and estimating the postmortem interval. 22,23 Raman spectroscopy can examine subtle biochemical alterations in certain pathophysiological mechanisms to diagnose associated diseases. 24,25 Infrared spectroscopy, another vibrational spectroscopy technique complementary to Raman spectroscopy, is also widely used in forensic research to identify injuries, histopathological changes, 26,27 and determine the cause of death.…”

Section: Introductionmentioning

confidence: 99%