Critical assessment of selenourea as an efficient small molecule fluorescence quenching probe to monitor protein dynamics

Abstract

This work unravels that reduced ΔE and higher −ve ΔG of the electron transfer reaction are crucial for an ultrafast intrinsic photoinduced electron transfer (PET) process that enables selenourea (SeU) as an efficient fluorescence quenching probe.

Post-synthetic modification of a covalent organic framework via a thiol–ene reaction for improving fluorescence detection and removal of cationic crystal violet carcinogenic dye

“…The differences are 2.7732 eV between the LUMO energies of COF-A and CV and 2.6668 eV between COF-S-COOH and CV, exceeding the energy range of 0.6 eV, blocking the PET process of both as electron donors to CV. 60 In conclusion, the mechanisms of CV quenching in COF-A and COF-S-COOH are consistent with the synergistic effect of dynamic and static quenching processes. The mechanism of the dynamic quenching process is FRET, while the mechanism of the static quenching process is IFE.…”

Selenoureido Calix[6]arenes: A Novel Platform for Pseudorotaxane Synthesis

“…[24] Selenourea compounds have some interesting aspects in this scenario since they could be considered good hydrogen bonding donors and acceptors because of a more delocalised electron density at the larger and polarisable selenium. [25][26][27][28] Based on these considerations and attracted by the scarcity of examples of seleniumcontaining macrocycles, [29][30][31][32][33][34][35] herein we report the synthesis and characterisation of a new triphenylselenoureido (TPSe) calix [6]arene heteroditopic receptor (Figure 1, b). Preliminary investigations on the complexation ability of this calix [6]arene wheel were also performed, suggesting its further application in the synthesis of interlocked rotaxane systems.…”