Critical care in obstetrics: pregnancy-specific conditions

Williams, Jennifer; Mozurkewich, Ellen; Chilimigras, Julie L.; Ven, Cosmas van de

doi:10.1016/j.bpobgyn.2008.06.003

Cited by 45 publications

(53 citation statements)

References 88 publications

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“…Warfarin should be given to postpartum women whose ejection fraction is 35% or less, and heparin or a low-molecularweight heparin should be given to women who are pregnant and have a similar ejection fraction. [41,42] Management of Decompensated Heart Failure in PPCM. [42,43] Maintaining airway, breathing and circulation of the patient are of the prime importance.…”

Section: Biomarkers and Diagnosis Of Ppcmmentioning

confidence: 99%

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Peripartum Cardiomyopathy: A Review

Jain¹,

Sikerwar²,

Rajpoot³

et al. 2016

jemds

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Peripartum Cardiomyopathy is a pregnancy associated rare but severe myocardial disease. The incidence of PPCM is about 1 in 3186 live births in United States. Causes include viral infections, toxins, environmental and geographic factors, familial predisposition, Hormonal abnormalities, haemodynamic burden of pregnancy, malnutrition, inflammation, etc. NT-proBNP, Cathepsin D, tyrosine kinase SFlt1 may be elevated and can be used as biomarkers to diagnose PPCM. Restriction of dietary sodium, beta-blockers, diuretics-thiazide and furosemide, in lowest possible doses can be given for symptomatic management. Prognosis of PPCM is positively related to the recovery of ventricular failure. Only about 50% women with PPCM recover baseline ventricular function within 6 months of delivery. Failure of heart size to return to normal is associated with increased mortality and morbidity. Future pregnancies are not recommended in patient with PPCM, as there is an increased risk for recurrence of PPCM in the subsequent pregnancy.

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Section: Biomarkers and Diagnosis Of Ppcmmentioning

confidence: 99%

“…[41,42] Management of Decompensated Heart Failure in PPCM. [42,43] Maintaining airway, breathing and circulation of the patient are of the prime importance. Intravenous loop diuretics, intravenous vasodilators (e.g.…”

Section: Biomarkers and Diagnosis Of Ppcmmentioning

confidence: 99%

Peripartum Cardiomyopathy: A Review

Jain¹,

Sikerwar²,

Rajpoot³

et al. 2016

jemds

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“…하지만 양수색전증 발생 후 생존 한 산모 중 신경학적 후유증이 남지 않는 경우는 단 15%에 불과하다 [10]. 또한 양수색전증 발생 시 주산기 사망률 (perinatal mortality)는 9-44%로 다양하게 보고되었는데 출혈 등과 같은 다른 질환을 배제함으로써 가능하다 [6,13].…”

Section: 빈도 및 모성사망 주산기 사망률과의 관계unclassified

Contemporary medical understanding of the 'no-fault accident' during birth: amniotic fluid embolism, pulmonary embolism, meconium aspiration syndrome, and cerebral palsy

Roh

2013

J Korean Med Assoc

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A lthough every pregnant woman and her physician hope for an easy pregnancy free of complications, complications can occur to a greater or lesser extent, some of which are still considered inevitable. The maternal mortality ratio in the Republic of Korea recently increased from 13.5 per 100,000 live births in 2009 to 17.2 in 2011, along with a noticeable increase, of up to 20%, in the proportion of older pregnant women (>35 years old). In contrast to postpartum bleeding, which has decreased, amniotic fluid embolism and pulmonary embolism, which are closely related to older maternal age and typically considered inevitable, are causing an increasing proportion of maternal mortalities. The neonatal mortality rate, defined the rate of death per 1,000 live births under 28 days of life, was reported to be 1.7 in 2011 in Korea and respiratory distress of newborns accounts for about one third of neonatal deaths. The prevalence of cerebral palsy (CP) is approximately 2 per 1,000 live-born children and has remained unchanged over recent decades worldwide. Although multiple antenatal factors, including preterm birth, low birth weight, infection/inflammation, multiple gestation, and other pregnancy complications have been frequently associated with CP, the underlying causes of CP remain largely unknown and recent evidence has indicated that birth asphyxia plays a minor role. This review provides information on the contemporary medical understanding of amniotic fluid embolism, pulmonary embolism, meconium aspiration syndrome, and CP, which are generally considered to be 'no-fault accidents' during birth.

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“…The majority of obstetric patients who require ICU admission suffer from complications of PPH, sepsis and hypertensive disorders (Naylor & Olson, 2003;Williams et al, 2008).…”

Section: Intensive Care Unit (Icu)mentioning

confidence: 99%