Critical Comparisons of the Clinical Performance of Oxygen-conserving Devices

Palwai, Aishwarya; Skowronski, Mary; Coreno, Albert; Drummond, Colin K.; McFadden, E.R.

doi:10.1164/rccm.200910-1638oc

Cited by 31 publications

(21 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Palwai et al 15 assessed the performance of 4 DOD systems, both in technical terms, in a bench study, and clinically, in 13 COPD subjects. Although all the devices tested were activated during nose and mouth breathing, there was poor synchronization between triggering and inspiration, and major discrepancies were found between the predicted and actual amounts of oxygen delivered.…”

Section: Discussionmentioning

confidence: 99%

“…7 Second, the higher breathing frequency in ILD subjects may place a stress on the mechanical performance of these devices, which are reported to have some technical limitations. 15 Although the DOD system we chose for the present study has good trigger sensi- Fig. 2.…”

Section: Discussionmentioning

confidence: 99%

“…However, our results support the notion that these systems may have limitations in certain groups of patients, as has been previously reported. 15 …”

Section: Discussionmentioning

confidence: 99%

“…When the patient is at rest, the 2 types of systems have proven to be equivalent. [9][10][11] However, when oxygen requirements increase, specifically during exercise [10][11][12][13][14][15][16] and in patients with ILD, 17 oxygenconserving devices do not seem to provide equivalent benefits.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?

Martí

Pajares²,

Morante³

et al. 2013

Respir Care

View full text Add to dashboard Cite

BACKGROUND: Correction of exercise hypoxemia in advanced lung diseases is crucial and often challenging. However, oxygen-conserving devices have been introduced in the market with limited evidence of effectiveness. In the present study the efficacy of 2 oxygen-conserving devices, a pulse demand oxygen delivery (DOD) system and pendant reservoir cannula (PRC), were evaluated in subjects with COPD and interstitial lung disease (ILD). METHODS: A cross-sectional, crossover study included 28 COPD and 31 ILD subjects with oxygen desaturation on the 6-min walk test (average S pO 2 < 88%). Each subject underwent 3 walk tests with DOD, PRC, and continuous oxygen flow by standard nasal cannula (CFNC), in random order, taking average S pO 2 > 90% as the resaturation criterion. RESULTS: Exercise desaturation was corrected in 79%, 79%, and 86% of COPD subjects with CFNC, DOD, and PRC, respectively, and in 77%, 61%, and 81% of ILD subjects with CFNC, DOD, and PRC, respectively. When compared to CFNC, the oxygen-conserving devices showed similar efficacy, except a lower performance for the DOD in the ILD subjects (P ‫؍‬ .01). CONCLUSIONS: Although these oxygen-conserving devices corrected exercise hypoxemia in most COPD and ILD subjects, correction was not achieved in about 20% of the severe COPD subjects, regardless of the device, and in nearly 40% of the ILD subjects with the DOD device. These findings underscore that individualized adjustment of oxygen flow is needed for optimal correction of exercise hypoxemia, especially with a DOD in an ILD patient. (Clinical Trials.gov NCT01086891).

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…However, our results support the notion that these systems may have limitations in certain groups of patients, as has been previously reported. 15 …”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?

Martí

Pajares²,

Morante³

et al. 2013

Respir Care

View full text Add to dashboard Cite

show abstract

“…7 For example, oxygen-conserving devices that use pulse-dose technology generally maintain adequate daytime and nighttime oxygenation, 8,9 but may be less efficient during periods of exercise and elevated breathing frequencies. 10 Oxygen-conserving devices using demand oxygen delivery require 2 sources, a stationary source and a portable source. 11 However, although such systems are more efficient, they are also more costly.…”

Section: Introductionmentioning

confidence: 99%

Oxygenation With a Single Portable Pulse-Dose Oxygen-Conserving Device and Combined Stationary and Portable Oxygen Delivery Devices in Subjects With COPD

Yáñez

Prat²,

Álvarez-Sala

et al. 2014

Respir Care

View full text Add to dashboard Cite

BACKGROUND: Portable oxygen devices simplify and facilitate patient therapy. This study was designed to compare S pO 2 and patient satisfaction with a portable oxygen concentrator or a combined system consisting of a fixed device with continuous-flow oxygen dispensation and a portable device with pulse dispensation for ambulation. METHODS: This crossover trial assessed 25 subjects with COPD (92% men, mean age of 72.2 ؎ 7.4 y, mean FEV 1 of 34.14 ؎ 12.51% of predicted) at 4 hospitals in Madrid. All subjects had previously used the combined system, consisting of a fixed oxygenation system and a portable system for ambulation, with 16 (64%) using stationary and portable concentrators and 9 (36%) using a stationary reservoir and portable liquid oxygen bag. Oxygenation settings at rest and while walking were determined at baseline. Subjects were maintained on the previous combined system for 1 week and then switched to the portable oxygen concentrator for 1 week. Mean S pO 2 over 24 h was calculated using the software in the oximeter, and compliance was monitored (Visionox). RESULTS: Low S pO 2 (< 90%) was significantly more frequent during use of the portable concentrator alone than with the combined system (37.1% vs 18.4%, P < .05). The portable system alone was preferred by 43% of subjects, and the combined system was preferred by 36%, whereas 21% were not sure. CONCLUSIONS: Subjects preferred using a single portable oxygenation system both at home and during ambulation. Portable systems alone, however, did not supply the same levels of oxygenation as the combination of fixed and portable systems. Before the widespread adoption of portable systems as a single device, additional studies are needed to determine best-practice protocols for adjustment of daytime and nighttime oxygenation settings. (ClinicalTrials.gov registration NCT02079753)

show abstract

Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy

Ekström

Ahmadi

Bornefalk-Hermansson

et al. 2016

Cochrane Database of Systematic Reviews

View full text Add to dashboard Cite

We are moderately confident that oxygen can relieve breathlessness when given during exercise to mildly hypoxaemic and non-hypoxaemic people with chronic obstructive pulmonary disease who would not otherwise qualify for home oxygen therapy. Most evidence pertains to acute effects during exercise tests, and no evidence indicates that oxygen decreases breathlessness in the daily life setting. Findings show that oxygen does not affect health-related quality of life.

show abstract

Critical Comparisons of the Clinical Performance of Oxygen-conserving Devices

Abstract: The mechanical and clinical performances of current oxygen conservers are highly variable and in some instances actually contribute to limitations in exercise ability. Seemingly equivalent technical features do not guarantee equivalent therapeutic functionality.

Cited by 31 publications

References 19 publications

Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?

Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?

Oxygenation With a Single Portable Pulse-Dose Oxygen-Conserving Device and Combined Stationary and Portable Oxygen Delivery Devices in Subjects With COPD

Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy

Contact Info

Product

Resources

About