“…Several studies have been associated with different methods of evaluation of the bio-compatibility of the prosthetic materials, in experimental 13,14,15,16,17,18,19 works and clinical 2,3,6,10,12,20,21,22 experimental Models allow detailed studies of these interactions, in the field of the anatomy, of the physiology, of the biochemistry, of the microbiology and of the mechanics, but little on tissue activity 13 .…”