Background:Industrial estates are one of the major centers of producing energy and industrial waste in the country.One of the important points of establishing industrial units in industrial towns and areas is to pay attention to industrial ecology; rotating economic policies with industrial ecological approach should be formed in industrial towns and the limitation of vital resources should never be neglected. The industry should be used as another industry input. Given that this trend and approach does not exist in Iran, this study seeks to investigate and analyze the factors influencing the launch of the industrial ecology perspective in Iran. Developing Industrial Ecology (IE) faces significant obstacles. However, the aim of this study is to evaluate the barriers due to a combination model, including DPSIR and Fuzzy Analytic Hierarchy Process (FAHP). To prioritize the responses (alternatives) regards to the driving forces, pressures, states, and impacts (criteria), the hierarchy of the model are established. In this research, for the purpose of identifying and prioritizing effective factors and analyzing research results, the opinions of 44 experts in the field of waste and environment, industrial engineering and industrial process were used.Result:In the first step of the results, based on the experts' point of view and study background and the experience of the last ten years of the world's leading countries, the general framework proposed by DPSIR for IE was presented. For the comparison of two fuzzy numbers, a novel division methods using concept was used. Due to the field studies, 18 criteria and four responses are suggested. Each of the main axes of the DPSIR model was carefully analyzed and in 4 radar diagrams, the analysis of each factor was presented. The first factor (R2) Improve IE law, with Final Weight (FW) 0.251, was selected as the first priority in the IE development model in Iran. Subsequent factors, in order of final weight, included (R3) Establish IE national database (0.246), (R4) Modify industries clustering (0.249) and (R1) Industries training (0.225).Conclusion:Industrial ecology in Iran has been failed to notices so far. The results males it crystal clear that the concepts of industrial ecology have not been implemented in Iran’s industrial estates. Based on the results of the analysis and the explanations provided, the proposed action plans for developing the industrial ecology model of Iran. This action provides a legal guarantee for the development of industrial ecology. Therefore, it can be said that the proposed route is the most reliable way to succeed based on current local and regional conditions in Iran.