Critical incidents in a French department of paediatric anaesthesia

Kupersztych-Hagege, Elisa; Duracher-Gout, Caroline; Ortego, R. Subirón; Carli, Pierre; Orliaguet, Gilles

doi:10.1016/j.accpm.2016.04.004

Cited by 10 publications

(9 citation statements)

References 27 publications

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“…Consistent with previous literature, multiple studies included in this review reported increased rate of medication error, critical incident, and/or cardiac arrest in patients <1 year of age . Several included studies found no association between age and risk of medication error or critical incident rate . Of note, the studies that did not find an association between age and risk had among the smallest sample sizes of those included in this review.…”

Section: Discussionsupporting

confidence: 77%

“…It is noteworthy that there is considerable heterogeneity with regard to the country in which the study took place, including European, North American, African, and Asian nations. Time period of patient observation is also an important source of heterogeneity among included studies.…”

Section: Discussionmentioning

confidence: 99%

“…Results are shown on a forest plot in Figure 1. All included studies 6,7,11,[13][14][15][16][17][18][19][20][21][22] 0.08% 0.05%-0.10% 94.08 0.0000…”

Section: Meta-analytic Estimate Of Medication Error Ratementioning

confidence: 99%

“…Data collected from one hospital only 7,11,[13][14][15][16][17][18][20][21][22] 0.11% 0.06%-0.16% 93.28 0.0000 ≥20 000 anesthetics 6,13,16,19,21,22 0.06% 0.04%-0.09% 95.68 0.0000 <20 000 anesthetics 7,11,14,17,18,20 0.36% 0.14%-0.58% 90.46 0.0000…”

Section: Meta-analytic Estimate Of Medication Error Ratementioning

confidence: 99%

“…It is noteworthy that there is considerable heterogeneity with regard to the country in which the study took place, including European, 7,[13][14][15][16] North American, 6,11,17 African, 18 and Asian [19][20][21][22] nations.…”

Section: Heterogeneity Of Studiesmentioning

confidence: 99%

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Frequency of medication error in pediatric anesthesia: A systematic review and meta‐analytic estimate

Feinstein

Pannunzio

Castro

2018

Pediatric Anesthesia

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Summary Background Clinical evidence shows that pediatric anesthesia patients are subject to a higher rate of life‐threatening medical errors than their adult counterparts. Medication error in adult anesthesia is estimated to occur to 1 in 133 anesthetic administrations, but such a figure has not been determined for pediatric anesthesia patients. Individual studies of medication error in pediatric anesthesia have ranged from rates of 0.01% to 1.92% of anesthetic uses. The present study is a systematic review that employs a meta‐analytic estimate to determine the rate of medication error in pediatric anesthesia. Methods A systematic review of the literature on pediatric anesthesia medication error was conducted using Medline, Cochrane Database, PROSPERO, and Clinicaltrials.gov. A meta‐analytic estimate was used to determine the medication error rate for all of the included studies. Subgroup sensitivity analysis was used to evaluate possible sources of heterogeneity in included studies. Results Of the 433 initially screened records, 13 studies met inclusion criteria. Meta‐analytic estimate of medication error rate across all studies was 0.08% (95% CI 0.05%‐0.10%), or 1 out of 1250 anesthetics. Ten different countries were represented in the studies. Sample size of anesthetics reported on ranged from 296 to 2 316 635. Data collecting periods ranged from 3 months to 15 years. Six included studies individually reported higher rates of medication error in patients under 1 year of age. Conclusion The present systematic review revealed a medication error rate of 1 per 1250 anesthetic administrations in pediatric anesthesia. This result is significantly lower than would be expected given reported rates of medication error in adult anesthesia, which raises questions regarding the validity of research methods and reporting of medication error in pediatric anesthesia. Future investigations of medication error should employ methodologies other than self‐reporting of error, such as retrospective chart review.

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Section: Discussionsupporting

confidence: 77%

Section: Discussionmentioning

confidence: 99%

“…Results are shown on a forest plot in Figure 1. All included studies 6,7,11,[13][14][15][16][17][18][19][20][21][22] 0.08% 0.05%-0.10% 94.08 0.0000…”

Section: Meta-analytic Estimate Of Medication Error Ratementioning

confidence: 99%