Critical patients COVID-19 has changed the management and outcomes in the ICU after 1 year of the pandemic? A multicenter, prospective, observational study

Rama-Maceiras, P.; Sanduende, Yolanda; Taboada, Manuel; Casero, María del Carmen Vidal; Leal, Sonsoles; Pita-Romero, Rafael; Fernández, Ricardo; López, Eva; López, José Antonio; Pita, E; Tubío, Ana; Rodríguez, Andrés Mauricio Quevedo; Varela, Marina; Campana, Daniel Perdigão; Delgado, Carla; Lombardía, Mónica; Villar, Eva; Blanco, Pilar; Martínez, Agustín; Sarmiento, Ana C.; Diaz, P.; Ojea, María José González; Rodríguez, Á. Jiménez; Mouriz, Lorena; Cid, Milagros; Ramos, Lorena; Seoane-Pillado, Teresa

doi:10.1016/j.eimce.2022.07.003

Cited by 2 publications

(3 citation statements)

References 45 publications

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“…Beyond the risk factors identified for a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection like male sex, older age, and comorbidities such as cardiovascular disease, lung disease or obesity, patients with a history of malignancy, specifically patients with haematological malignancy, are prone to develop a complicated SARS-CoV-2 infection with need for ICU which is still associated with poorer clinical outcome [ 2 – 15 ]. The circumstances of a widely heterogenous population with regards to the type of haematological malignancy, extent of disease, haematological malignancy treatment history, [ 16 – 18 ] and baseline performance status are even more challenging in the environment of an ICU [ 19 ]. Although, data referring to critically ill COVID-19 patients regarding treatment strategies and outcome are widely available, data referring to critically ill patients with haematological malignancy are scarce and underreported [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Need for ICU and outcome of critically ill patients with COVID-19 and haematological malignancies: results from the EPICOVIDEHA survey

Lahmer,

Salmanton-García,

Marchesi

et al. 2024

Infection

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Section: Introductionmentioning

confidence: 99%

Need for ICU and outcome of critically ill patients with COVID-19 and haematological malignancies: results from the EPICOVIDEHA survey

Lahmer,

Salmanton-García,

Marchesi

et al. 2024

Infection

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“…One explanation could be the change in ventilation strategy over time. Several studies found increased use of NIMV during the second wave, with a significant increase in use of high‐flow nasal cannula 13,27–30 . One study found an increase in NIMV in older patients associated with increased mortality 27 .…”

Section: Discussionmentioning

confidence: 99%

“…Several studies found increased use of NIMV during the second wave, with a significant increase in use of high-flow nasal cannula. 13,[27][28][29][30] One study found an increase in NIMV in older patients associated with increased mortality. 27 In our review, we did not analyze the data according to the different waves because of too few studies were exclusively performed during the second wave.…”

Section: Discussionmentioning

confidence: 99%

Mortality in older patients admitted to an ICU for COVID‐19: A systematic review

Bianco

Guidet

Dechartres

et al. 2023

Acta Anaesthesiol Scand

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PurposeThe objective was to conduct a systematic review of mortality and factors independently associated with mortality of older patients admitted to an intensive care unit (ICU) for COVID‐19.Materials and MethodsData sources were MEDLINE, EMBASE, the Cochrane Library, and references of included studies. Two reviewers independently selected studies evaluating mortality of older patients (≥ 70 years) admitted to an ICU for COVID‐19. They extracted general characteristics, mortality rate, and factors independently associated with mortality. The methodological quality of each study was evaluated by using the Critical Appraisal Skills Programme checklist.ResultsWe selected 36 studies (11,989 patients). Many of the studies were conducted in Europe (42%) and many were retrospective (61%) and multicenter (61%). ICU mortality ranged from 8% to 90%, 1‐month mortality from 33% to 90% and 3‐month mortality, reported in five studies, from 46% to 60%. Frailty, assessed by the Clinical Frailty Score (CFS), was significantly associated with 1‐month and 3‐month mortality respectively in two studies (hazard ratio [HR]: 3.2 [2.56–4.13] and HR: 2.83 [95% CI: 1.96–4.08]).ConclusionIn this systematic review of older patients admitted to an ICU with COVID‐19, we documented high heterogeneity of mortality rates.

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Critical patients COVID-19 has changed the management and outcomes in the ICU after 1 year of the pandemic? A multicenter, prospective, observational study

Cited by 2 publications

References 45 publications

Need for ICU and outcome of critically ill patients with COVID-19 and haematological malignancies: results from the EPICOVIDEHA survey

Need for ICU and outcome of critically ill patients with COVID-19 and haematological malignancies: results from the EPICOVIDEHA survey

Mortality in older patients admitted to an ICU for COVID‐19: A systematic review

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Critical patients COVID-19 has changed the management and outcomes in the ICU after 1 year of the pandemic? A multicenter, prospective, observational study

Cited by 2 publications

References 45 publications

Need for ICU and outcome of critically ill patients with COVID-19 and haematological malignancies: results from the EPICOVIDEHA survey

Need for ICU and outcome of critically ill patients with COVID-19 and haematological malignancies: results from the EPICOVIDEHA survey

Mortality in older patients admitted to an ICU for COVID‐19: A systematic review

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Critical patients COVID-19 has changed the management and outcomes in the ICU after 1 year of the pandemic? A multicenter, prospective, observational study