Critical Period Plasticity Matches Binocular Orientation Preference in the Visual Cortex

Wang, Bor Shuen; Sarnaik, Rashmi; Cang, Jianhua

doi:10.1016/j.neuron.2010.01.002

Cited by 198 publications

(297 citation statements)

References 67 publications

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“…Half of the complex phase of ͚R()e 2i /͚R() was calculated and then converted to stimulus orientation in the range of 0 -180 (Wang et al, 2010a).…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, orientation/direction-selective responses were seen in the dLGN of awake mice (n ϭ 8/14 had OSI or DSI Ͼ 0.5, as in the example shown in Fig. 1B To further characterize the tuning properties of orientation-selective cells (OSI Ն 0.33, as widely used in the studies of mouse cortical selectivity: Wang et al, 2010a;Liu et al, 2011), we quantified their tuning widths and preferred orientations. The tuning widths distributed between 20°and 50°in most cells, with a median of 37.7°( Fig.…”

Section: Orientation-and Direction-selective Responses In the Mouse Dlgnmentioning

confidence: 99%

“…Visual stimuli were generated with a Matlab Psychophysics toolbox (Pelli, 1997), as described previously (Niell and Stryker, 2008;Wang et al, 2010a). Stimuli were presented using a CRT monitor (60 Hz refresh rate, ϳ35 cd/m 2 luminance) placed 25 cm away and in front of the animal.…”

Section: In Vivo Extracellular Recording and Visual Stimulimentioning

confidence: 99%

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Orientation-selective Responses in the Mouse Lateral Geniculate Nucleus

Zhao

Chen

Liu

et al. 2013

Journal of Neuroscience

130

121

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The dorsal lateral geniculate nucleus (dLGN) receives visual information from the retina and transmits it to the cortex. In this study, we made extracellular recordings in the dLGN of both anesthetized and awake mice, and found that a surprisingly high proportion of cells were selective for stimulus orientation. The orientation selectivity of dLGN cells was unchanged after silencing the visual cortex pharmacologically, indicating that it is not due to cortical feedback. The orientation tuning of some dLGN cells correlated with their elongated receptive fields, while in others orientation selectivity was observed despite the fact that their receptive fields were circular, suggesting that their retinal input might already be orientation selective. Consistently, we revealed orientation/axis-selective ganglion cells in the mouse retina using multielectrode arrays in an in vitro preparation. Furthermore, the orientation tuning of dLGN cells was largely maintained at different stimulus contrasts, which could be sufficiently explained by a simple linear feedforward model. We also compared the degree of orientation selectivity in different visual structures under the same recording condition. Compared with the dLGN, orientation selectivity is greatly improved in the visual cortex, but is similar in the superior colliculus, another major retinal target. Together, our results demonstrate prominent orientation selectivity in the mouse dLGN, which may potentially contribute to visual processing in the cortex.

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“…Half of the complex phase of ͚R()e 2i /͚R() was calculated and then converted to stimulus orientation in the range of 0 -180 (Wang et al, 2010a).…”

Section: Discussionmentioning

confidence: 99%

Section: Orientation-and Direction-selective Responses In the Mouse Dlgnmentioning

confidence: 99%

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Orientation-selective Responses in the Mouse Lateral Geniculate Nucleus

Zhao

Chen

Liu

et al. 2013

Journal of Neuroscience

130

121

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“…Sensory experiences during the "critical period" have major and long-lasting impacts on brain processing that have been argued to enable individuals to adapt to a wide range of environments (Berardi et al, 2000;Hensch, 2004;Knudsen, 2004;Dahmen and King, 2007;Sanes and Bao, 2009;Wang et al, 2010). In the auditory system, previous studies have documented a well defined, acoustic environment-dependent critical period in the primary auditory cortex (A1) in the rat (Zhang et al, 2001;de VillersSidani et al, 2007;Insanally et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Natural Restoration of Critical Period Plasticity in the Juvenile and Adult Primary Auditory Cortex

Zhou¹,

Panizzutti²,

Villers-Sidani³

et al. 2011

J. Neurosci.

104

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Since its first description Ͼ40 years ago, the neurological "critical period" has been predominantly described as an early, plastic postnatal brain development stage that rather abruptly advances to an aplastic or less plastic "adult" stage. Here, we show that chronic exposure of juvenile or adult rats to moderate-level acoustic noise results in a broad reversal of maturational changes that mark the infant-to-adult progression in the primary auditory cortex. In time, noise exposure reinstates critical period plasticity. Cortical changes resulting from noise exposure are again reversed to reestablish a physically and functionally normal adult cortex, by returning animals to natural acoustic environments. These studies show that at least some of neurological changes believed to mark the transition from the infantile to the mature (adult) stage are, by their nature, reversible.

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“…Lack of visual experience during the CP for visual cortex refinements can, for example, cause irreversible visual impairment (8). Refinements during the CP play an essential role (9). Although some functions can be substantially ameliorated after the CP, they are rarely optimally restored.…”

mentioning

confidence: 99%

Progressive maturation of silent synapses governs the duration of a critical period

Huang

Stodieck

Goetze

et al. 2015

Proc. Natl. Acad. Sci. U.S.A.

100

172

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During critical periods, all cortical neural circuits are refined to optimize their functional properties. The prevailing notion is that the balance between excitation and inhibition determines the onset and closure of critical periods. In contrast, we show that maturation of silent glutamatergic synapses onto principal neurons was sufficient to govern the duration of the critical period for ocular dominance plasticity in the visual cortex of mice. Specifically, postsynaptic density protein-95 (PSD-95) was absolutely required for experience-dependent maturation of silent synapses, and its absence before the onset of critical periods resulted in lifelong juvenile ocular dominance plasticity. Loss of PSD-95 in the visual cortex after the closure of the critical period reinstated silent synapses, resulting in reopening of juvenile-like ocular dominance plasticity. Additionally, silent synapse-based ocular dominance plasticity was largely independent of the inhibitory tone, whose developmental maturation was independent of PSD-95. Moreover, glutamatergic synaptic transmission onto parvalbumin-positive interneurons was unaltered in PSD-95 KO mice. These findings reveal not only that PSD-95-dependent silent synapse maturation in visual cortical principal neurons terminates the critical period for ocular dominance plasticity but also indicate that, in general, once silent synapses are consolidated in any neural circuit, initial experience-dependent functional optimization and critical periods end.

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Critical Period Plasticity Matches Binocular Orientation Preference in the Visual Cortex

Cited by 198 publications

References 67 publications

Orientation-selective Responses in the Mouse Lateral Geniculate Nucleus

Orientation-selective Responses in the Mouse Lateral Geniculate Nucleus

Natural Restoration of Critical Period Plasticity in the Juvenile and Adult Primary Auditory Cortex

Progressive maturation of silent synapses governs the duration of a critical period

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