Abstract:Objective: Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder characterized by rest tremors, bradykinesia, rigidity, postural instability, gait dysfunction, and several non-motor symptoms. The marked difference in drug response and adverse effect profile among patients led to search of genetic markers and polymorphism associated with response to antiparkinsonian drugs which will enable us to predict an individual's response to drugs in terms of both efficacy and toxicity. Hence, effor… Show more
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