Critical review on quality of methodology and recommendations of clinical practice guidelines for peri-implantitis

Yin, Qiaofeng; Liang, Jingyi; Zhang, Yuhang; Chen, Canxiong; Yu, Weiming; Wang, Xiaoyi; Ji, Jianxin

doi:10.1186/s12903-023-02904-4

Cited by 3 publications

(2 citation statements)

References 32 publications

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“…Two independent experts used the Appraisal of Guidelines for Research and Evaluation (AGREE) II [22,23]. This solution is well-known, proven and has been frequently used to date to evaluate medical devices and procedures [24][25][26][27][28], including exoskeletons [29]. The PubMed database shows 1231 publications with the keyword "AGREE II".…”

Section: Methodsmentioning

confidence: 99%

Personalization of the 3D-Printed Upper Limb Exoskeleton Design—Mechanical and IT Aspects

et al. 2023

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The human hand is the most precise and versatile tool that nature has given man, and any deficits in this area affect the functional capabilities and quality of human life. Scientists, engineers and clinicians are constantly looking for solutions in the field of diagnosis, treatment, rehabilitation and care of patients with hand function deficits. One such solution is a hand exoskeleton. In the process of designing and testing the hand exoskeleton, emphasis should be placed on the full usability and comfort of the system; hence, the issues of personalization, matching and testing are crucial for the development of the discussed group of solutions. The aim of this paper is to present the possibilities of personalizing 3D-printed medical devicesbased on our own experience in functional user assessment andthe material selection, design, optimization using artificial intelligence and production and testing of several generations of different upper limb exoskeletons, incorporatingthe considerations of the Medical Device Regulation (MDR), ISO 13485 and ISO 10993 standards.The novelty and possible contribution of the proposed approach consist of the possibilities and limitations of the personalization of the upper limb exoskeleton discussed in the article as well as the directions of further development of significant scientific, technical and clinical importance.

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Section: Methodsmentioning

confidence: 99%

Personalization of the 3D-Printed Upper Limb Exoskeleton Design—Mechanical and IT Aspects

et al. 2023

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“…Micro-CT is a common method for analyzing alveolar bone loss. Vertical bone loss, which is assessed by measuring the linear distance between the implant neck and the lowest point of the alveolar bone, was used to evaluate alveolar bone destruction around implants (Yin et al, 2023). The results showed that the composite hydrogels with ultrasound stimulation group exhibited significantly less bone destruction than the peri-implantitis group (Figure 6C).…”

Section: In Vivo Inflammatory Regulation and Bone Repair Analysismentioning

confidence: 99%

A sono-responsive antibacterial nanosystem co-loaded with metformin and bone morphogenetic protein-2 for mitigation of inflammation and bone loss in experimental peri-implantitis

Hu,

Qiao,

Cao

et al. 2024

Front. Bioeng. Biotechnol.

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BackgroundDental implants have become an increasingly popular option for replacing missing teeth, and the prevalence of peri-implantitis has also increased, which is expected to become a public health problem worldwide and cause high economic and health burdens. This scenario highlights the need for new therapeutic options to treat peri-implantitis.MethodsIn this study, we proposed a novel sono-responsive antibacterial nanosystem co-loaded with metformin (Met) and bone morphogenetic protein-2 (BMP-2) to promote efficacy in treating peri-implantitis. We introduced the zeolitic imidazolate framework-8 (ZIF-8) as a carrier for hematoporphyrin monomethyl ether (HMME) to enhance the antibacterial effect of sonodynamic antibacterial therapy and tested its reactive oxygen species (ROS) production efficiency and bactericidal effect in vitro. Afterward, HMME-loaded ZIF-8, BMP-2-loaded polylactic acid-glycolic acid (PLGA), and Met were incorporated into gelatin methacryloyl (GelMA) hydrogels to form HMME@ZIF-8/Met/BMP-2@PLGA/GelMA composite hydrogels, and the biocompatibility of which was determined in vitro and in vivo. A bacterial-induced peri-implantitis model in the maxilla of rats was established to detect the effects of the composite hydrogels with adjunctive use of ultrasound on regulating inflammation and promoting bone tissue repair in vivo.ResultsThe results indicated that HMME@ZIF-8 with ultrasound stimulation demonstrated more better ROS production efficiency and antimicrobial efficacy. The composite hydrogels had good biocompatibility. Ultrasound-assisted application of the composite hydrogels reduced the release of the inflammatory factors IL-6 and TNF-α and reduced bone loss around the implant in rats with bacterial-induced peri-implantitis.ConclusionOur observations suggest that HMME@ZIF-8 may be a new good sonosensitizer material for sonodynamic antibacterial therapy. The use of HMME@ZIF-8/Met/BMP-2@PLGA/GelMA composite hydrogels in combination with ultrasound can provide a novel option for treating peri-implantitis in the future.

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Clinical and Microbiological Results of Complex Treatment of Dental Periimplantitis

Burlakova,

Gizinger,

Muraev

et al. 2024

Actual Problems in Dentistry

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Clinical and laboratory studies were conducted in 24 patients with chronic dental periimplantitis before and after complex treatment aimed at destroying biofilms on the surface of the dental implant to prevent indirect infection. The aim of the study is to develop a comprehensive, etiologically based treatment regimen for dental peri-implantitis based on correction of the oral microbiota. The study was based on indicators of secretory immunoglobulin A (IgA) and an analysis of the composition of the microbiome of mixed saliva in patients with healthy implants and peri-implantitis. A new conceptual approach to the diagnosis and pathogenetically based comprehensive treatment of dental peri-implantitis is proposed. At the first stage, a peri-implantitis treatment regimen was performed according to the protocol “The EFP S3 level clinical practice guideline”. After performing this standard treatment for 6 weeks, we have proposed a scheme that includes: 1) the drug for inhibiting the bacterial film “ACC LONG” 600 mg (Hermes Pharma, Germany) – in the form of oral baths for 2 minutes 30 minutes before meals; 2) for the purpose of adhesion and sorption of biofilm elements – Chitosan succinate (Active+ drug, GREEN VOICE, Russia) after meals in rinsing method: dosage of 10–12 drops per 250 ml of liquid; 3) for the purpose of probiotic correction of oral microbiocenosis, the drug BIFIDUM BAG (5 ml dissolved in water no higher than 40 °C) for 20–30 minutes topically in the form of mouth baths, then swallow after eating for one month. It was found that with the progression of peri-implantitis, there is a decrease in the level of secretory IgA and a decrease in local resistance of the oral cavity to pathogenic influences. The standard treatment regimen helps to stabilize inflammation in the area of dental implants, but does not lead to a sustained positive effect.

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Critical review on quality of methodology and recommendations of clinical practice guidelines for peri-implantitis

Cited by 3 publications

References 32 publications

Personalization of the 3D-Printed Upper Limb Exoskeleton Design—Mechanical and IT Aspects

Personalization of the 3D-Printed Upper Limb Exoskeleton Design—Mechanical and IT Aspects

A sono-responsive antibacterial nanosystem co-loaded with metformin and bone morphogenetic protein-2 for mitigation of inflammation and bone loss in experimental peri-implantitis

Clinical and Microbiological Results of Complex Treatment of Dental Periimplantitis

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