Critical values of hematocrit and mixed venous oxygen saturation as parameters for a safe cardiopulmonary bypass

Osawa, Hiroshi; Yoshii, Shinpei; Abraham, S; Hosaka, Shigeru; Suzuki, Shoji; Ogata, Koji; Akashi, Okihiko; Higuchi, Hiroji; Tada, Yusuke

doi:10.1007/s11748-004-0083-2

Cited by 6 publications

(2 citation statements)

References 18 publications

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“…52 Osawa and colleagues performed an animal study to evaluate the safe levels for hematocrit and mixed venous oxygen saturation on CPB and found hematocrit level >12% and SvO 2 >46% to be “safe” for CPB. 53 In a study of patients undergoing CPB, Ranucci and colleagues identified the lowest hematocrit of 26% associated with increased renal impairment outcomes that allows an oxygen delivery of 262 mL/min/m 2 . 54…”

Section: Anesthetic Managementmentioning

confidence: 99%

Anesthetic Management for Cardiopulmonary Bypass

Bechtel

Huffmyer

2014

Semin Cardiothorac Vasc Anesth

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Cardiopulmonary bypass has revolutionized the practice of cardiac surgery and allows safe conduct of increasingly complex cardiac surgery. A brief review of the bypass circuit is undertaken in this review. A more thorough review of the anesthetic management is accomplished including choice of anesthetic medications and their effects. The inflammatory response to cardiopulmonary bypass is reviewed along with interventions that may help ameliorate the inflammation.

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Section: Anesthetic Managementmentioning

confidence: 99%

Anesthetic Management for Cardiopulmonary Bypass

Bechtel

Huffmyer

2014

Semin Cardiothorac Vasc Anesth

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“…These techniques are a major step toward a more effective and reliable production of blood products 1 , 2 . Also, extracorporeal circulation circuits such as hemodialysis 3 or cardiopulmonary bypass 4 are now widely available techniques to treat blood in-vitro. In these various cases, blood flows in sterile tubing, where it is difficult to monitor continuously its properties such as hematocrit without extracting a blood sample.…”

Section: Introductionmentioning

confidence: 99%

Exploitation of blood non-Newtonian properties for ultrasonic measurement of hematocrit

Pialot

Gachelin²,

Provost

et al. 2021

Sci Rep

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New processing techniques for manipulating blood and its components at a microfluidic scale are currently implemented. As for extracorporeal circulation, the in-line evaluation and monitoring of blood properties during these microfluidic techniques is a challenging task. Here, we show that the blood hematocrit can be measured non-invasively in a sub-millimeter medical tube using the non-Newtonian behavior of blood velocity profile. This hematocrit measurement is demonstrated on human blood with a simple Doppler ultrasound system. Results show a mean measurement error of 4.6 ± 1.3%Hct for hematocrit up to 52% and for 5 s-long ultrasonic signals. The simplicity and the measurement scale of the approach make it highly valuable for measuring hematocrit in new blood separation techniques. The approach may have an impact on in-vitro blood processing in general.

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