Crohn's disease and Sweet's syndrome: an uncommon association

Catalán-Serra, Ignacio; Martín-Moraleda, L.; Navarro-López, Luz Patricia; Gil-Borrás, Rafael; Pont-Sanjuan, Virginia; Ferrando-Marco, J.; Herrera-García, L.; Durbán-Serrano, L.; Hontangas-Pla, V.; Benlloch, Salvador; Escudero-Sanchis, A.; Gonzalvo-Sorribes, J. M.; Bixquert-Jiménez, M.

doi:10.4321/s1130-01082010000500009

Cited by 21 publications

(18 citation statements)

References 15 publications

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“…SS diagnosis is confirmed when two major criteria and at least two minor criteria are met. 1 In the present case, despite the absence of neutrophilic infiltrates in the biopsy, the patient was diagnosed with SS since all the other criteria were positive, and histopathological findings were compatible with the histiocytic variant.…”

Section: Discussionmentioning

confidence: 50%

“…8 It may also occur in association with infections – particularly with respiratory and gastrointestinal tract infections – and autoimmune diseases such as Behçet's disease, Hashimoto's thyroiditis, and inflammatory bowel disease. 1 …”

Section: Discussionmentioning

confidence: 99%

“…1 In general, skin lesions appear in the active phase of the disease and can, in 20% of cases, precede intestinal symptoms. In addition, other extra-intestinal manifestations may be present in patients with this association, especially joint involvement.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, other extra-intestinal manifestations may be present in patients with this association, especially joint involvement. 1,8 …”

Section: Discussionmentioning

confidence: 99%

“…1,2 It is generally associated with other diseases, such as infections, inflammatory diseases, connective tissue diseases, and cancer. 1,3 However, its association with Crohn's disease (CD) is rare, with only 40 cases reported in the literature. 3 A systematic review published in 2002 revealed no reports of this association in Brazil.…”

Section: Introductionmentioning

confidence: 99%

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Sweet's syndrome associated with Crohn's disease

Lima

Pinto

Góes

et al. 2017

An. Bras. Dermatol.

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Sweet's syndrome is an uncommon benign skin disorder, whose pathogenesis remains unknown. Its classic form is more common in women and presents itself as papular-nodular, painful and erythematous or violaceous lesions. It mainly affects the face, neck, and upper limbs. Fever and neutrophilic leukocytosis are also common features. Although it is considered a systemic disease marker in more than half of patients, the association of this condition with Crohn's disease is rare, with few cases reported in the literature, of which, none in Brazil. We report the case of a patient with Crohn's disease who developed the classical features of Sweet's syndrome.

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Section: Discussionmentioning

confidence: 50%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…In addition, other extra-intestinal manifestations may be present in patients with this association, especially joint involvement. 1,8 …”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Sweet's syndrome associated with Crohn's disease

Lima

Pinto

Góes

et al. 2017

An. Bras. Dermatol.

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Neutrophilic Dermatoses

Ormerod,

Hampton

2016

Rook's Textbook of Dermatology, Ninth Edition

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Pyoderma gangrenosum is a rare, non‐infectious, neutrophilic dermatosis commonly associated with underlying systemic disease. Diagnosis is based on typical clinical features and the exclusion of other cutaneous ulcerating diseases. It is most often encountered as the classic type but several variants also need to be distinguished. Its course may be protracted and recurrent with significant morbidity and mortality. Milder cases can respond to simple topical measures but frequently, potent immunosuppressive therapies, combined therapies or biologicals including antitumour necrosis factor treatment are required to achieve healing.

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Neutrophilic Dermatoses

Hampton,

Ball

2024

Rook's Textbook of Dermatology

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The neutrophilic dermatoses are a collection of non‐infectious dermatoses involving triggering of inflammation in the context of a reduced threshold for neutrophilic inflammation. Genetic factors have been identified in rare cases and numerous predisposing diseases play a role. They are best described as autoinflammatory conditions whereby the triggering of the inflammatory process begins with abnormal activation of the innate immune system, distinct from an autoimmune process involving T cells or antibody production. Two classical neutrophilic dermatoses exist. Pyoderma is distinguished by the tendency for ulceration and tissue destruction. Sweet syndrome is generally more time limited with full recovery expected. Multiple variants exist and the optimal treatment strategies have not been agreed.

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Crohn's disease and Sweet's syndrome: an uncommon association

Cited by 21 publications

References 15 publications

Sweet's syndrome associated with Crohn's disease

Sweet's syndrome associated with Crohn's disease

Neutrophilic Dermatoses

Neutrophilic Dermatoses

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