Crohn’s disease in total knee arthroplasty patients correlates with increased rates of 90-day and overall postoperative complications and readmissions

Inflammatory bowel disease is associated with an increased risk of adverse events in patients undergoing joint arthroplasty

“…The included studies were all conducted in the USA. Six studies collected data from nationwide administrative databases, 5,18,19,[21][22][23] and two from a single-centre hospital database. 20,24 Five studies reported mixed cohorts of patients suffering from IBD 5,[19][20][21]24 and three included patients with CD only.…”

“…20,24 Five studies reported mixed cohorts of patients suffering from IBD 5,[19][20][21]24 and three included patients with CD only. 18,22,23 One study investigated hip, knee, and shoulder arthroplasty, 21 two investigated hip and knee arthroplasty, 5,24 two investigated total knee arthroplasty only, 22,23 and three investigated total hip arthroplasty only. [18][19][20] The International Classification of Diseases, Ninth/Tenth Revision (ICD-9/10) diagnosis codes were used to diagnose IBD in seven studies.…”

“…[18][19][20] The International Classification of Diseases, Ninth/Tenth Revision (ICD-9/10) diagnosis codes were used to diagnose IBD in seven studies. 5,18,19,[21][22][23][24] Five studies used ICD-9 procedural codes or Current Procedural Terminology codes to identify patients undergoing joint arthroplasty. 5,18,[21][22][23] Three preoperative risk assessment tools were used, including the Charlson Comorbidity Index, 24 Charlson Deyo Index, 22 and Elixhauser Comorbidity Index.…”

“…5,18,19,[21][22][23][24] Five studies used ICD-9 procedural codes or Current Procedural Terminology codes to identify patients undergoing joint arthroplasty. 5,18,[21][22][23] Three preoperative risk assessment tools were used, including the Charlson Comorbidity Index, 24 Charlson Deyo Index, 22 and Elixhauser Comorbidity Index. 18,19,21,23 Postoperative follow-up period was within 90 days of surgery in four studies, 5,18,21,23 whereas medium-term or long-term follow-up (2 to 8.9 years) was reported in four studies.…”

“…16,17 Recently, several studies have been published investigating the potential impact of IBD on postoperative outcomes in patients undergoing joint arthroplasty. 5,[18][19][20][21][22][23][24][25] These studies produced conflicting results, making it essential to take an evidence-based approach to synthesize the cohort data and draw more concrete conclusions in the context of modern surgical practice. To the best of our knowledge, no systematic review or meta-analysis has been performed to date to evaluate the impact of coexisting IBD on the clinical outcomes in joint arthroplasty patients.…”