Cross Calibration of the GE Prodigy and iDXA for the Measurement of Total and Regional Body Composition in Adults

Oldroyd, B.; Treadgold, Laura A.; Hind, Karen

doi:10.1016/j.jocd.2017.05.009

Cited by 14 publications

(10 citation statements)

References 23 publications

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“…The values for lean mass, fat mass, fat percent (%), and BMD for both whole body and regional area were measured in both DXA machines. Scan mode selection was automatically processed by the manufacturer's software for GE Lunar Prodigy and array mode was used for Hologic Horizon W scanner following each manufacturer's protocol for body composition measures [20][21][22]. The results were analyzed using GE Lunar encore version 13.60 or Hologic APEX software 5.6.0.4.…”

Section: Article In Pressmentioning

confidence: 99%

Comparison of Two DXA Systems, Hologic Horizon W and GE Lunar Prodigy, for Assessing Body Composition in Healthy Korean Adults

et al. 2021

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Background: Dual-energy X-ray absorptiometry (DXA) is the most widely used method for evaluating muscle masses. The aim of this study was to investigate the agreement between muscle mass values assessed by two different DXA systems.Methods: Forty healthy participants (20 men, 20 women; age range, 23 to 71 years) were enrolled. Total and regional body compositional values for fat and lean masses were measured consecutively with two DXA machines, Hologic Horizon and GE Lunar Prodigy. Appendicular lean mass (ALM) was calculated as the sum of the lean mass of four limbs.Results: In both sexes, the ALM values measured by the GE Lunar Prodigy (24.8±4.3 kg in men, 15.8±2.9 kg in women) were significantly higher than those assessed by Hologic Horizon (23.0±4.0 kg in men, 14.8±3.2 kg in women). Furthermore, BMI values or body fat (%), either extremely higher or lower levels, contributed greater differences between two systems. Bland-Altman analyses revealed a significant bias between ALM values assessed by the two systems. Linear regression analyses were performed to develop equations to adjust for systematic differences (men: Horizon ALM [kg]=0.915×Lunar Prodigy ALM [kg]+0.322, R2=0.956; women: Horizon ALM [kg]=1.066×Lunar Prodigy ALM [kg]–2.064, R2=0.952).Conclusion: Although measurements of body composition including muscle mass by the two DXA systems correlated strongly, significant differences were observed. Calibration equations should enable mutual conversion between different DXA systems.

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Section: Article In Pressmentioning

confidence: 99%

Comparison of Two DXA Systems, Hologic Horizon W and GE Lunar Prodigy, for Assessing Body Composition in Healthy Korean Adults

et al. 2021

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“…No significant changes were observed in extracellular water, and there were no significant differences between FPH doses or the whey protein isolate control for all measured endpoints. Measures of lean mass, fat-free mass, and bone mineral content by DXA were not reported; hence, the contributions of these tissues to the overall body weight reductions, as per the three-compartment model [91], are unclear. From these data, it is inconclusive that the FPH had any impact on body composition as the observed changes are likely attributable to the caloric deficit achieved through alimentary diaries.…”

Section: Body Compositionmentioning

confidence: 99%

The Potential Role of Fish-Derived Protein Hydrolysates on Metabolic Health, Skeletal Muscle Mass and Function in Ageing

Lees

Carson

2020

Nutrients

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Fish protein represents one of the most widely consumed dietary protein sources by humans. The processing of material from the fishing industry generates substantial unexploited waste products, many of which possess high biological value. Protein hydrolysates, such as fish protein hydrolysates (FPH), containing predominantly di- and tripeptides, are more readily absorbed than free amino acids and intact protein. Furthermore, in animal models, FPH have been shown to possess numerous beneficial properties for cardiovascular, neurological, intestinal, renal, and immune health. Ageing is associated with the loss of skeletal muscle mass and function, as well as increased oxidative stress, compromised vascularisation, neurological derangements, and immunosenescence. Thus, there appears to be a potential application for FPH in older persons as a high-quality protein source that may also confer additional health benefits. Despite this, there remains a dearth of information concerning the impact of FPH on health outcomes in humans. The limited evidence from human interventional trials suggests that FPH may hold promise for supporting optimal body composition and maintaining gut integrity. FPH also provide a high-quality source of dietary protein without negatively impacting on subjective appetite perceptions or regulatory hormones. Further studies are needed to assess the impact and utility of FPH on skeletal muscle health in older persons, ideally comparing FPH to ‘established’ protein sources or a non-bioactive, nitrogen-matched control. In particular, the effects of acute and chronic FPH consumption on post-exercise aminoacidaemia, skeletal muscle protein synthesis, and intramyocellular anabolic signalling in older adults are worthy of investigation. FPH may represent beneficial and sustainable alternative sources of high-quality protein to support skeletal muscle health and anabolism in ageing, without compromising appetite and subsequent energy intake.

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“…[11] Advances in densitometric technology have been made over the last few decades, including replacing pencil beams with fan https://doi.org/10.11005/jbm.2021.28.3.215 beams, higher output X-ray tubes, reduced pixel size, multiple detectors, wider transverse scanning widths, faster scanning times, improved accuracy, and scanning beds to accommodate higher body weights for patients. [12] However, as different instruments are developed, the measurement values of the various devices differ. [6,13] Therefore, many studies have been conducted to develop a conversion formula to analyze the differences between the various instruments and for calibrating the measurement values between the different devices.…”

Section: Introductionmentioning

confidence: 99%

“…[ 11 ] Advances in densitometric technology have been made over the last few decades, including replacing pencil beams with fan beams, higher output X-ray tubes, reduced pixel size, multiple detectors, wider transverse scanning widths, faster scanning times, improved accuracy, and scanning beds to accommodate higher body weights for patients. [ 12 ]…”

Section: Introductionmentioning

confidence: 99%

Cross-Calibration of Bone Mineral Densities and Body Composition between GE Lunar Prodigy and Osteosys Primus

Yoo

2021

J Bone Metab

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Background: The aim of this study was to investigate the correlation between bone mineral density (BMD) and body composition measured by the Osteosys Primus® and the GE Lunar Prodigy® and to calculate the conversion rate between the 2 devices.Methods: The 40 subjects were men and women in aged 20 to 29 years old. All participants were scanned twice on both the Osteosys Primus (OsteoSys) and the GE Lunar Prodigy (GE Healthcare) DXA systems using the manufacturers’ standard scanning and positioning protocols.Results: Compared to the GE Lunar device, the mean Osteosys fat mass was overestimated to be 12.1% (1,776.9 g) in the whole body, 5.1% (163.9 g) in gynoid, and 6.7% (87.2 g) in android. Compared with the GE Lunar device, the mean BMDs of the Osteosys Primus were underestimated to be 2.3% (0.023 g/cm2) in the whole body and 3.1% (0.035 g/cm2) in L1-4. Compared with the GE Lunar device, the mean lean mass derived by the Osteosys Primus were underestimated to 2.3% (1,045.3 g) in the total body, 3.8% (179.4 g) in arms, and 7.7% (1,104.8 g) in legs, respectively. There were a strong correlation of BMD and body composition between both groups.Conclusions: Linear correction equations were developed to ensure comparability of BMD and muscle mass between the Osteosys Primus and the GE Lunar Prodigy. Importantly, use of equations from previous studies would have increased the discrepancy between the Osteosys Primus and the GE Lunar Prodigy.

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Cross Calibration of the GE Prodigy and iDXA for the Measurement of Total and Regional Body Composition in Adults

Cited by 14 publications

References 23 publications

Comparison of Two DXA Systems, Hologic Horizon W and GE Lunar Prodigy, for Assessing Body Composition in Healthy Korean Adults

Comparison of Two DXA Systems, Hologic Horizon W and GE Lunar Prodigy, for Assessing Body Composition in Healthy Korean Adults

The Potential Role of Fish-Derived Protein Hydrolysates on Metabolic Health, Skeletal Muscle Mass and Function in Ageing

Cross-Calibration of Bone Mineral Densities and Body Composition between GE Lunar Prodigy and Osteosys Primus

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