Quantum blockade and entanglement play important roles in quantum information and quantum communication as quantum blockade is an effective mechanism to generate single photons (phonons) and entanglement is a crucial resource for quantum information processing. In this work, we propose a method to generate single entangled photon-phonon pairs in a hybrid optomechanical system. We show that photon blockade, phonon blockade, and photon-phonon correlation and entanglement can be observed via the atom-photon-phonon (tripartite) interaction, under the resonant atomic driving. The correlated and entangled single photons and single phonons, i.e., single entangled photonphonon pairs, can be generated in both the weak and strong tripartite interaction regimes. Our results may have important applications in the development of highly complex quantum networks.