Cross-cultural Adaptation and Validation of the Medication Regimen Complexity Index Adapted to Spanish

Abstract

The MRCI-E retains the reliability and validity of the original index and provides a suitable tool to assess the complexity of medication regimens in Spanish.

Validation and standardization of the Brazilian version of the Medication Regimen Complexity Index for older adults in primary care

“…Therefore, the observed correlation between this variable and MRCI scores confirms the convergent validity of the tool. Similar results were observed in the tool’s adaptation studies to Brazilian Portuguese, German, Spanish and Turkish, 24 in which there were also significant correlations between MRCI scores and the number of prescribed medications.…”

“…This result corroborates the importance of using a validated tool, consisting of realms that evaluate different aspects of pharmacotherapy for the measurement of complexity . Thus, medication number alone is not sufficient to measure the level of difficulty of using a medication therapy . Pharmacotherapy with fewer medications, but with a high frequency of daily administration, might be more complex than a pharmacotherapy with a greater number of medications, all administered only once a day …”

“…In this context, factors such as age, sex, cognition or functional characteristics do not contribute to the scores of complexities obtained by the MRCI. In the MRCI adaptation studies to Spanish and Turkish, there were also no significant correlations between the tool’s scores and the characteristics of age and sex, and between MRCI and sex in the study of adaptation to Brazilian Portuguese …”

“…Thus, medication number alone is not sufficient to measure the level of difficulty of using a medication therapy . Pharmacotherapy with fewer medications, but with a high frequency of daily administration, might be more complex than a pharmacotherapy with a greater number of medications, all administered only once a day …”

“…26 Thus, medication number alone is not sufficient to measure the level of difficulty of using a medication therapy. [14][15][16][17][18][19][20][21][22][23][24][25][26][27] Pharmacotherapy with fewer medications, but with a high frequency of daily administration, might be more complex than a pharmacotherapy with a greater number of medications, all administered only once a day. 28 Reliability analyses showed an excellent agreement between the scores obtained by the same and by different evaluators.…”