ObjectiveMuscle tension in the head and neck may co‐occur with temporomandibular dysfunction (TMD) possibly leading to voice change. Several studies have reported a correlation between TMD and dysphonia. However, literature on TMD and voice‐related quality of life (QOL) is scant. This study aimed to investigate the relationship between TMD and self‐perceived voice‐related QOL impairment.MethodsPatients from TMD clinic were prospectively surveyed on voice‐related quality of life using the Voice Handicap Index (VHI) questionnaire. Patients were queried using paper and pen upon initial evaluation in dentistry clinic for temporomandibular disorders by a single dentist or dental assistant in the otolaryngology department.ResultsA total of 53 patients completed the VHI. 80% of patients presenting to TMD clinic had VHI scores above zero, but most had minimal to mild impairment. Forty‐two patients had scores between 1 and 86, (average 10.98); 11 patients had a score of zero (20.75%). Total average score: 8.70, range: 0–86, median: 4. Functional average score: 3.13, range: 0–29, median: 1. Physical average score: 3.58. range: 0–25, median: 2. Emotional average score: 1.98, range: 0–32, median: 0; these averages did not differ from historical controls.ConclusionThe majority of patients presenting to TMD clinic also presented with some level of voice‐related QOL impairment, although minimal and consistent with historical VHI controls. Data indicates that TMD disease may be primarily defined as functionally and physically uncomfortable. Incorporation of interdisciplinary care, with laryngology, speech pathology, physical therapy, counseling, and pain management may be warranted.Level of Evidence4 Laryngoscope, 2023