Cross-geographic region differences in quality of life in women with and without vertebral fracture

Schoor, Natasja M. van; Yu, Hai; Bobula, JD; Lips, Paul

doi:10.1007/s00198-009-0853-x

Cited by 8 publications

(3 citation statements)

References 23 publications

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“…Other authors con rm our results that well-paid work improves the quality of life assessed in the QUALEFFO 41 scale in women with postmenopausal osteoporosis [17]. The literature reports show that the factors signi cantly related to quality of life were body mass index (BMI), race, school education, age at menopause and implementation of hormone therapy [17]. Osteoporosis reduces the patient's quality of life by affecting all spheres of the patient's life.…”

Section: Discussionsupporting

confidence: 71%

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Quality of Life in Women With Postmenopausal Osteoporosis - Pilot Studies in the Łódź Province

Górczewska

Jakubowska-Pietkiewicz²

2020

Preprint

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BackgroundOsteoporosis is a social disease and epidemic of the 21st century, and is also a growing problem in the ageing Polish society. The aim of the study was to assess the quality of life (QoL) in women with postmenopausal osteoporosis. MethodsThe study was an outpatient, questionnaire-based poll, carried out from VI.2018 to V.2019. A group of 198 women, aged 72.31±8.59 years with diagnosed postmenopausal osteoporosis in two Osteoporosis Clinics in the city of Łódź (Poland) were included. The paper uses: the Polish version of the QUALEFFO 41 quality of life scale, the VAS scale and a survey of my own authorship. The data were analysed using multiple linear regression.ResultsThe average result of QUALEFFO-41 was 40.26±16.92 points. Analysing individual QUALEFFO-41 domains the lowest quality of life was found in the mental function domain (mental function 48.49±18.06 points). The visual analogue scale of pain was 4.87±2.39 points. The VAS scale positively correlated with all QUALEFFO 41 domains. Marital status, education and financial situation had a significant statistical impact on the quality of life (p<;0.05). Multiple regression step-by-step analysis showed that pain expressed on the VAS scale, pain awakening from sleep, taking sleeping pills and older age of respondents deteriorate the quality of life.ConclusionThe analysis showed that Polish women with postmenopausal osteoporosis have an average quality of life. In Poland the assessment of quality of life of chronically ill patients and routine evaluation of pain severity on the VAS scale is not common.

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Section: Discussionsupporting

confidence: 71%

“…al. [17,18]. This can be explained by the fact that women with higher education usually look for more information about their illness (they broaden their knowledge) [18], so that they take supplements more often (e.g.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life in Women With Postmenopausal Osteoporosis - Pilot Studies in the Łódź Province

Górczewska

Jakubowska-Pietkiewicz²

2020

Preprint

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“…The specific instruments most widely used include the Osteoporosis Quality of Life Questionnaire (OQLQ) [6,7] and its reduced version the mini-OQLQ [8], the Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO) [9,10], the Osteoporosis Assessment Questionnaire (OPAQ) [11,12], the Osteoporosis-Targeted Quality of Life Questionnaire (OPTQoL) [13,14] and the assessment of health-related quality of life in osteoporosis (ECOS-16) [15]. Among the generic instruments, those most used in osteoporotic patients includes the EuroQol 5-D (EQ5D) [16,17], the Medical Outcomes Study Survey Form (MOS-SF) in its SF-12 [18] or SF-36 [16] versions that could be combined with the disease-specific module Quality of Life in Osteoporosis (QUALIOST)[19,20], and the Health Utility Index [7,21]. …”

Section: Introductionmentioning

confidence: 99%

Impact of osteoporosis and vertebral fractures on quality-of-life. a population-based study in Valencia, Spain (The FRAVO Study)

Sanfélix-Genovés

Hurtado

Sanfélix‐Gimeno

et al. 2011

Health and Quality of Life Outcomes

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BackgroundTo describe the health related quality of life in a population sample of postmenopausal women over the age of 50 and resident in the city of Valencia (Spain), according to the presence/absence of osteoporosis and the severity of prevalent morphometric vertebral fractures.MethodsA cross-sectional age-stratified population-based sample of 804 postmenopausal women of 50 years of age and older were assessed with the SF-12 questionnaire. Information about demographic features, lifestyle, clinical features, educational level, anti-osteoporotic and other treatments, comorbidities and risk factors for osteoporosis were collected using an interviewer-administered questionnaire and densitometric evaluation of spine and hip and spine x-rays were carried out.ResultsIn the non-adjusted analysis, mild and moderate-severe vertebral fractures were associated with decreased scores in the SF-12 Physical Component Summary (PCS) but not in the Mental Component Summary (MCS), while densitometric osteoporosis with no accompanying fracture was not associated with a worse health related quality of life. In multivariate analysis worse PCS scores were associated to the age groups over 70 (-2.43 for 70-74 group and -2.97 for 75 and older), chronic conditions (-4.66, -6.79 and -11.8 according to the presence of 1, 2 or at least 3 conditions), obesity (-5.35), peripheral fracture antecedents (-3.28), hypoestrogenism antecedents (-2.61) and the presence of vertebral fracture (-2.05).ConclusionsAfter adjusting for confounding factors, the physical components of health related quality of life were significantly lower in women with prevalent osteoporotic vertebral fractures than in women -osteoporotic or not- without vertebral fractures.

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Health-related quality of life in patients with osteoporosis in the absence of vertebral fracture: a systematic review

2012

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To review whether osteoporosis in the absence of vertebral fracture (VFX) affects health-related quality of life (HRQoL), a systematic search of the main literature databases for HRQoL in patients with osteoporosis without VFX was undertaken. This was undertaken. This identified 1,327 articles as potentially relevant to the review. After screening of abstracts and reviewing 168 articles in detail, 27 were considered relevant. HRQoL data were extracted and collated into tables and, where possible, were converted into normative scores and further analysed. Data relating to the associations between HRQoL and bone mineral density (BMD) were also collated. Of the 27 articles included, only 5 directly compared osteoporosis without VFX with a control group (BMD T-score > -1.0, without VFX). Extracted raw data from 21 articles demonstrated that patients with osteoporosis without VFX had clinically relevant reductions in role physical, general health, vitality, mental health domains and the mental component summary score, using SF36. Using Qualeffo-41, pain and physical function were worse in these patients. Also, HRQoL was related to upper femur, but not lumbar spine BMD. HRQoL data in patients with osteoporosis without VFX are limited and variable but suggest that HRQoL is adversely affected by osteoporosis in the absence of VFX. The association of lower BMD and worse HRQoL suggests that more attention should be paid to HRQoL in those without VFX. Future studies are needed to investigate HRQoL in patients with osteoporosis in the absence of fracture, controlling for co-morbidities and social and economic status.

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Cross-geographic region differences in quality of life in women with and without vertebral fracture

Cited by 8 publications

References 23 publications

Quality of Life in Women With Postmenopausal Osteoporosis - Pilot Studies in the Łódź Province

Quality of Life in Women With Postmenopausal Osteoporosis - Pilot Studies in the Łódź Province

Impact of osteoporosis and vertebral fractures on quality-of-life. a population-based study in Valencia, Spain (The FRAVO Study)

Health-related quality of life in patients with osteoporosis in the absence of vertebral fracture: a systematic review

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