Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human

Song, Huai‐Dong; Tu, Changchun; Zhang, Guowei; Wang, Shengyue; Zheng, Kui; Lei, Liancheng; Chen, Qiuxia; Gao, Yuwei; Zhou, Huiqiong; Xiang, Hua; Zheng, Huajun; Chern, Shur-Wern Wang; Cheng, Feng; Pan, Chun-Ming; Huang, Xuan; Chen, Sai‐Juan; Luo, Hai‐Bin; Zhou, Dun-Jin; Liu, Yu-Fei; He, Jianfeng; Qin, Pengzhe; Li, Ling-Hui; YuQi, Ren; Liang, Wenjia; Yu, Yao; Anderson, Larry J.; Wang, Ming; Xu, Ruiheng; Wu, Xinwei; Zheng, Huanying; Chen, Jinding; Liang, Guodong; Gao, Yang; Liao, Ming-Hui; Fang, Ling; Jiang, Liyun; Li, Hui; Chen, Fang; Di, Biao; Li, He; Lin, Junyu; Tong, Suxiang; Kong, Xiangang; Du, Lanying; Hao, Pei; Tang, Hua; Bernini, Andrea; Yu, Xiao-Jing; Spiga, Ottavia; Guo, Zong-Ming; Pan, Haiyan; He, Weiming; Manuguerra, Jean-Claude; Fontanet, Arnaud; Danchin, Antoine; Niccolai, Neri; Li, Yixue; Wu, Chung‐I; Zhao, Guoping

doi:10.1073/pnas.0409608102

Cited by 652 publications

(701 citation statements)

References 24 publications

Supporting

Mentioning

654

Contrasting

Unclassified

Order By: Relevance

“…However, several lines of evidence suggested that the civets may have served only as an amplification host for SARS-CoV and provided the environment for efficient interspecies transmissions. First, the Ka͞Ks ratios (rate of nonsynonymous mutation͞rate of synonymous mutation) of the S, orf3a, and nsp3 genes of the civet strains in both the 2003 and the minor 2004 outbreaks were high, suggesting a rapidly evolving process of gene adaptation in the animals (10). Second, although the S proteins of SARS-CoV isolated from humans during the 2003 epidemic were shown to bind to and use both human and palm-civet ACE2 efficiently, isolates from the 2004 minor outbreaks and those from palm civets used human ACE2 markedly less efficiently (11).…”

Section: Discussionmentioning

confidence: 99%

“…Most differences between the bat-SARS-CoV genomes and human and civet SARS-CoV genomes were observed in the S gene, ORF 3, and ORF 8 (Table 4), which also were the regions where most variations were observed in human SARS-CoV and civet SARSCoV genomes (10). Compared with SARS-CoV from humans and civets, there were 11 insertions and 15 deletions in the bat-SARS-CoV genome, located in the 5Ј noncoding region, nsp3 of ORF 1ab, S gene, ORF 3, and ORF 8.…”

Section: Wild Animal Surveillance Identification Of Bat-sars-cov Anmentioning

confidence: 99%

“…However, subsequent studies suggested that the civet may have served only as an amplification host for SARS-CoV and provided the environment for major genetic variations permitting efficient animal-tohuman and human-to-human transmissions (10)(11)(12)(13). Because civets are often mixed with different species in overcrowded conditions at markets, we conducted a surveillance study for CoV in noncaged animals from the wild areas of the Hong Kong Special Administrative Region (HKSAR).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats

Lau

Woo

et al. 2005

Proc. Natl. Acad. Sci. U.S.A.

1,427

1,425

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Wild Animal Surveillance Identification Of Bat-sars-cov Anmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats

Lau

Woo

et al. 2005

Proc. Natl. Acad. Sci. U.S.A.

1,427

1,425

View full text Add to dashboard Cite

“…raccoon dogs, masked palm civets and hog badger and spilling over to human population through close contact with these animals or their tissues. Later on adaptive mutations in virus genome lead to human to human transmission of virus (Song et al, 2005).…”

Section: Sars-cov Like Virusesmentioning

confidence: 99%

Bats: carriers of zoonotic viral and emerging infectious diseases

Ranjan¹,

Prasad²,

Prasad³

2016

JEBAS

View full text Add to dashboard Cite

“…Further scattered outbreaks of the infection were reported late in 2003 and early in 2004 in Singapore, Taiwan, Beijing and Guangzhou. All of them were linked to the cases of laboratory contamination and virus transmission from animals to humans [9], after the ban was lifted to sell palm civets in wet markets and serve palm civet dishes in restaurants imposed during the atypical pneumonia outbreak [10].…”

Section: New Coronavirusesmentioning

confidence: 99%

Emergence of new infections in the 21st century and identification of pathogens using next generation sequencing

et al. 2017

View full text Add to dashboard Cite

Каждое новое инфекционное заболевание может быть серьезным вызовом для современной медицины. Измене-ние окружающей среды, вырубка тропических лесов, таяние льдов в Антарктике, увеличение плотности населения и повсеместное использование антибиотиков -все это факторы, провоцирующие появление новых патогенов. Эпидемии гриппа, вызываемые новыми штаммами вируса; респираторные синдромы, вызываемые новыми коро-навирусами; вспышки инфекций, причиной которых является гемолитическая кишечная палочка; возникновение резистентных к антибиотикам супербактерий -примеры того, какие опасности могут поджидать человечество. В число первоочередных мер, которые необходимо предпринять для противодействия новым патогенам, входит раз-работка способов их быстрой и точной идентификации. В обзоре рассмотрены случаи возникновения в XXI веке новых инфекционных агентов, а также проанализированы возможность и перспективы использования для выявления и идентификации новых патогенов методов высокопроизводительного секвенирования (next generation sequence).Ключевые слова: инфекционные агенты, патогенные организмы, методы выявления новых патогенов, высокопроиз-водительное секвенирование, коронавирус, вирус гриппа, горизонтальный перенос генов, антибиотикорезистентность CENTURY AND IDENTIFICATION OF PATHOGENS USING NEXT GENERATION SEQUENCINGEach new emerging infection may become a big challenge to the medical community. Changing environment, tropical deforestation, melting of the Antarctic ice, growing population density and uncontrolled use of antibiotics provoke emergence and evolution of pathogens. Epidemics caused by new strains of the influenza virus, respiratory syndromes associated with coronaviruses, outbreaks of hemolytic Escherichia coli infections and antibiotic-resistant superbacteria are hazards to humans. Among high-priority measures for pathogen control that are yet to be taken is development of fast and accurate techniques for pathogen identification. Our review looks at the cases of new infections registered in the 21 st century and explores feasibility of next generation sequencing for the detection and identification of new pathogens.

show abstract

Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human

Cited by 652 publications

References 24 publications

Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats

Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats

Bats: carriers of zoonotic viral and emerging infectious diseases

Emergence of new infections in the 21st century and identification of pathogens using next generation sequencing

Contact Info

Product

Resources

About