“…3) Small data alleviation with weak supervision, semisupervision or self-supervision strategies: The current image segmentation algorithms mostly rely on the availability of large amount of training data with pixel-level annotations, which are often expensive, tedious, and laborious. To alleviate the labeling burden and small data limitation, the past years have witnessed an increasing attention in building label-efficient deep segmentation algorithms [12], [70], [71]. According to the supervision provided by different types of labeling, deep learning methods with weak supervision, semi-supervision, or self-supervision strategies are explored to alleviate the problem of medical data limitation in data-driven deep learning.…”