Cross-reactivity between MUC1 antigen and MCA: false elevation of serum CA 15-3 level in pregnant and lactating women by Ma695–Ma552-based assay

Liang, Guangshu; Fang, Xing; Lin, Xiaojuan; Feng, Xiaojing; Lu, Huangying; Wan, Yinglei; Gu, Zhidong

doi:10.1007/s10549-018-4700-7

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2019

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“…Liang et al [23] found that serum CA 15-3 levels detected by Ma695-Ma552-based assay was abnormally and significantly higher both in pregnant and in lactating women than in non-pregnant women. This study suggests caution when interpreting the results, taking into account what kind of laboratory assay was used.…”

Section: Literature Reviewmentioning

confidence: 99%

Can we trust tumour markers in pregnancy after breast cancer? A case of elevated CA 15-3 in the third trimester of pregnancy normalising after delivery

Buonomo

Noli

Santini

et al. 2019

ecancer

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We realized a narrative review of the current literature starting from the case of a patient with raised CA15-3 during an uncomplicated pregnancy after breast cancer. The aim of our paper was to assess specificity, physiological changes and clinical utility of CA 15-3 monitoring during pregnancy after breast cancer, starting from clinical practice and retrieving the most relevant evidence in the literature.

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Section: Literature Reviewmentioning

confidence: 99%

Can we trust tumour markers in pregnancy after breast cancer? A case of elevated CA 15-3 in the third trimester of pregnancy normalising after delivery

Buonomo

Noli

Santini

et al. 2019

ecancer

View full text Add to dashboard Cite

show abstract

Cross-reactivity between MUC1 antigen and MCA: false elevation of serum CA 15-3 level in pregnant and lactating women by Ma695–Ma552-based assay

Abstract: The CA 15-3 assay using 115D8-DF3 antibody pair is more suitable for monitoring therapy in pregnancy-associated breast cancer.

Cited by 1 publication

References 28 publications

Can we trust tumour markers in pregnancy after breast cancer? A case of elevated CA 15-3 in the third trimester of pregnancy normalising after delivery

Can we trust tumour markers in pregnancy after breast cancer? A case of elevated CA 15-3 in the third trimester of pregnancy normalising after delivery

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