Cross-sectional area of the vagus nerve on carotid duplex ultrasound and atrial fibrillation in acute stroke: A retrospective analysis

Oura, Kazumasa; Itabashi, Ryo; Oura, Mao Yamaguchi; Kiyokawa, Tetsuro; Hirai, Eisuke; Maeda, Tetsuya

doi:10.1016/j.ensci.2021.100378

Cited by 6 publications

(3 citation statements)

References 20 publications

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“…All patients underwent VN ultrasonography, performed by four experienced technicians blinded to the patient's diagnosis. The VN CSA was measured as in previous studies, 15,18 at the level of the thyroid gland using high-resolution ultrasound (Aplio i700, Canon Medical Systems, Otawara, Japan) and a 12-MHz linear probe. The VN was scanned in the axial view, and the optimal settings for gain, depth, and focus were used for each patient (Fig.…”

Section: Vagus Nerve Ultrasonographymentioning

confidence: 99%

Vagus Nerve Ultrasonography Helps Distinguish Multiple System Atrophy from Other Parkinsonian Syndromes

Oura

Yamaguchi

Nozaki

et al. 2023

Movement Disord Clin Pract

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BackgroundDistinguishing multiple system atrophy from other parkinsonian syndromes is challenging.ObjectivesTo evaluate vagus nerve ultrasonography for differentiating parkinsonian syndromes.MethodsA single‐center, cross‐sectional, observational study assessed 85 consecutive adult patients with de novo parkinsonism between June 2020 and December 2022, using 12 MHz ultrasonography of the vagus nerve cross‐sectional area.ResultsBilateral vagus nerves were smaller in multiple system atrophy than in other parkinsonian syndromes. The area under the receiver operating characteristic curve for differentiating multiple system atrophy was 0.79 on the right side and 0.74 on the left. The cut‐off values to diagnose multiple system atrophy were 0.71 and 0.86 mm2 on the right and left sides, respectively, with sensitivities of 82.6% and 87.0%, specificities of 74.2% and 64.5%, positive predictive values of 54% and 47.6%, and negative predictive values of 92.0% and 93.0%.ConclusionsVagus nerve ultrasonography may differentiate multiple system atrophy from other parkinsonian syndromes.This article is protected by copyright. All rights reserved.

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Section: Vagus Nerve Ultrasonographymentioning

confidence: 99%

Vagus Nerve Ultrasonography Helps Distinguish Multiple System Atrophy from Other Parkinsonian Syndromes

Oura

Yamaguchi

Nozaki

et al. 2023

Movement Disord Clin Pract

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“…Additionally, utilization of ultrasound of the VN has been documented for the use in various diseases including diabetes mellitus, Parkinson's disease, multifocal motor neuropathy, chronic inflammatory demyelinating polyradiculoneuropathy, amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, systemic vasculitic neuropathy, and atrial fibrillation. [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] Moreover, VN stimulation for the management of epilepsy has gained popularity in the last few years. [25] Furthermore, VN stimulation has been documented for the management of intractable hiccoughs (hiccups).…”

Section: Introductionmentioning

confidence: 99%

Ultrasound of the normal vagus nerve cross-sectional area in the carotid sheath

et al. 2023

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The aim of this article is to utilize ultrasound to evaluate the normal cross-sectional area (CSA)of the vagus nerve (VN) in the carotid sheath. This study included 86 VNs in 43 healthy subjects (15 men, 28 women); mean age 42.1 years and mean body mass index 26.2 kg/m2. For each subject, the bilateral VNs were identified by US at the anterolateral neck within the common carotid sheaths. One radiologist obtained 3 separate CSA measurements for each of the bilateral VNs with complete transducer removal between each measurement. Additionally, for each participant, demographic information of age and gender as well as body mass index, weight, and height were documented. The mean CSA of the right VN in the carotid sheath was 2.1 and 1.9 mm2 for the left VN. The right VN CSA was significantly larger than the left VN (P < .012). No statistically significant correlation was noted in relation to height, weight, and age. We believe that the reference values for the normal CSA of the VN obtained in our study, could help in the sonographic evaluation of VN enlargement, as it relates to the diagnosis of various diseases affecting the VN.

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“…In addition, Liu et al [ 13 ] showed enlargement of the VN on both sides in a cohort of northern Chinese patients with Guillain-Barré syndrome subtypes; the VN was larger in patients exhibiting autonomic dysfunction. Furthermore, recently, we have shown the cross-sectional area (CSA) of the VN on the right side to be an independent predictor of atrial fibrillation (AF) in a cohort of Japanese patients following acute ischemic stroke or transient ischemic attack [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Ultrasound evaluation of vagus nerve cross-sectional area in a community-dwelling elderly Japanese cohort

et al. 2023

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Objectives Although the vagus nerve (VN) is easily observed by ultrasonography, few studies have evaluated the cross-sectional area (CSA) of the VN in healthy older individuals from East Asia. In this study, we aimed to report reference values for the CSA of the VN in community-dwelling elderly Japanese individuals and to identify any associated medical history and/or lifestyle factors. Methods The present study included 336 participants aged ≥ 70 years from a prospective cohort study conducted in Yahaba, Japan from October 2021 to February 2022. The CSA of the VN was measured bilaterally at the level of the thyroid gland by ultrasonography. Simple linear regression analysis and generalized estimating equation were conducted to identify the associations between clinical and background factors and the CSA of the VN. Results In our cohort, the median CSA of the VN was 1.3 mm2 (interquartile range [IQR] 1.1–1.6) on the right side and 1.2 mm2 (IQR 1.0–1.4) on the left side. Generalized estimating equation showed that history of head injury (β = 0.19, p < .01), current smoking habit (β = -0.09, p = .03), and BMI (β = 0.02, p < .01) were independently associated with the CSA of the VN. Conclusion We have reported reference VN CSA values for community-dwelling elderly Japanese individuals. In addition, we showed that the CSA of the VN was positively associated with a history of head injury and BMI and inversely associated with current smoking habit.

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Cross-sectional area of the vagus nerve on carotid duplex ultrasound and atrial fibrillation in acute stroke: A retrospective analysis

Cited by 6 publications

References 20 publications

Vagus Nerve Ultrasonography Helps Distinguish Multiple System Atrophy from Other Parkinsonian Syndromes

Vagus Nerve Ultrasonography Helps Distinguish Multiple System Atrophy from Other Parkinsonian Syndromes

Ultrasound of the normal vagus nerve cross-sectional area in the carotid sheath

Ultrasound evaluation of vagus nerve cross-sectional area in a community-dwelling elderly Japanese cohort

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