Cross-sectional community-based study of the socio-demographic factors associated with the prevalence of dengue in the eastern part of Sudan in 2011

Abstract

BackgroundDengue is caused by an arthropod-borne flavivirus. Infection can be either primary or secondary based on serology, with each stage of the disease characterized by specific serological conversion and antibody formation. Further study is needed to fully identify the factors associated with and predisposing to dengue infection. The objective of this study was to identify socio-demographic factors associated with the prevalence of dengue serotypes in Kassala State in the eastern part of Sudan in 2011.MethodsThis was a cross-sectional community-based study with 530 participants who were randomly selected through multi-stage cluster sampling. Dengue serotype prevalence was determined using capture Enzyme-linked immunosorbent assay (ELISA). ELISA IgG. A multivariate logistic regression model was designed to measure the strength of associations between socio-demographic factors and dengue serotype prevalence. All participants who tested negative for dengue were used as the statistical reference group.ResultsFrom this study, the prevalence of dengue in Kassala was estimated to be 9.4 % (95 % CI: 7.1–12.3). Lack of knowledge about dengue fever disease (OR 2.8, 95 % CI: 1.24–6.53) and a household density of more than 3 people per room (OR 2.1, 95 % CI: 1.06–4.09) were the most important factors associated with dengue infection among the study population.ConclusionsCommunity-oriented interventions are needed to modify existing social behaviors to reduce the risk of dengue in the eastern part of Sudan. Additional studies are also required in this field.

Prevalence and identification of arthropod-transmitted viruses in Kassala state, Eastern Sudan

“…The PCR reveals negative results. Although not all these viruses were responsible for VHF, we screening these viruses due to many studies were conducted in eastern Sudan revealed the presence of highly seropositive of dengue and HEV [33,[43][44][45]. Thirteen patients were positive for dengue IgM in ELISA, although the PCR results for all DFV types were negative, which may be explained by the presence of several genetically and antigenically different serotypes of the DFV worldwide [6,7,43,[46][47][48].…”

Recent transmission of dengue virus and associated risk Facors among residents of Kassala state, eastern Sudan

“…The high incidence of the disease has become of great concern to the public health officers worldwide [7][8][9]. In the recent years, DENV has spread all over the Sudan resulting in frequent occurrence of sporadic cases and multiple outbreaks [10][11][12][13]. The major economic losses caused by DENV infections in Sudan are almost exclusively confind to the Kassala state, eastern Sudan [10,11,[14][15][16].…”

Dengue seroprevalence and its socioeconomic determinants in Faisalabad, Pakistan: a cross-sectional study

“…Another important factor in the transmission of dengue infection in this study was persons-per-room, which indirectly measures host density or overcrowding. The reason lies behind the behavior of the dengue vector, which feeds on several individuals in a given time 2 , therefore increasing the risk of transmission of dengue virus to several individuals in households with a higher number of persons per room 13 . Overcrowding is always associated with poverty and lower socioeconomic status, making it an important social predictor of dengue infection 14 .…”