Cross-sectional Imaging in Crohn Disease

Furukawa, Akira; Saotome, Takao; Yamasaki, Michimasa; Maeda, Koki; Nitta, Norihisa; Takahashi, Masashi; Tsujikawa, Tomoyuki; Fujiyama, Yoshihide; Murata, Kiyoshi; Sakamoto, Tetsuya

doi:10.1148/rg.243035120

Cited by 228 publications

(132 citation statements)

References 37 publications

Supporting

Mentioning

108

Contrasting

Unclassified

Order By: Relevance

“…This sequence, known as true fast imaging with steady-state precession (true-FISP), presents with an intermediate contrast between T1-and T2-weighted images [29,[31][32][33] . Shorter repetition times (TR) are used (< 3 m) and the acquisition time is short.…”

Section: Sequencesmentioning

confidence: 99%

“…Chronic inflammatory disease, and in particular, CD, represents the most common application of MRI of small bowel [1][2][3][4][5]8,9,15,[28][29][30][31][32][33][34][35]38] .…”

Section: Inflammatory Bowel Disease (Cd) (Figures 1-4)mentioning

confidence: 99%

“…Scores ranging from 0 to approximately 600 with values below 150 are considered as remission and values over 150 as active disease. MR imaging was used to evaluate disease activity [9,[30][31][32][33][34][35]38,41,44,48,49] . Based on different experiences, contrast-enhanced(CE) fat-suppressed T1-weighted images offer the best correlation between MR findings and CDAI, although a correlation that used fatsuppressed T2-weighted images is also demonstrated.…”

Section: Assessment Of Disease Activitymentioning

confidence: 99%

“…Inactive disease is characterized by no abnormalities or bowel wall thickening with relative low signal intensity representing fibrosis with limited, homogeneous contrast enhancement. Absence of stratification on T2-weighted images with stratified enhancement on T1-weighted images is often due to fibrosis, which is a typical longstanding CD [29,33,35,44] . This sign (stratified enhancement) also can be seen on MSCT (multi-slice CT) images [45,46] .…”

Section: Imaging Findingsmentioning

confidence: 99%

See 3 more Smart Citations

Updating magnetic resonance imaging of small bowel: Imaging protocols and clinical indications

Zhu¹,

Xu²,

Gong³

et al. 2008

WJG

View full text Add to dashboard Cite

High soft tissue contrast resolution, acquisition of multi-planar images and the possibility to obtain functional information make magnetic resonance an interesting imaging technique to evaluate the small bowel disease. The absence of ionizing radiation is an important feature of magnetic resonance imaging (MRI) examinations because inflammatory diseases such as Crohn's disease (CD) are studied most frequently, which are prevalent among children and young adults. MRI, using modern equipment and a rigorous technical approach, can offer detailed morphologic information and functional data on the small bowel. This article discusses the MRI protocols for small bowel and the MR imaging findings of small bowel diseases, such as CD and small bowel neoplasms. There are two main approaches for MRI of the small bowel: (1) study following oral administration of contrast material; and (2) study with distension of lumen obtained with contrast material that is introduced through a naso-jejunal tube (MR enteroclysis). Oral contrast agents for small bowel MRIOral contrast agents can be classified into positive, negative and biphasic categories according to their action on the signal intensity of bowel lumen.A positive agent is a paramagnetic substance that produces a high signal intensity on T1-weighted sequences. It reduces T1 relaxation time without, or only minimally, influencing T2 relaxation time. Because of the water content of the contrast solution, it also results in high signal intensity on T2-weighted images. Positive contrast agents include paramagnetic substances, such as gadolinium chelates, ferrous and manganic ions and manganese ions [12][13][14][15][16] . The use of positive oral contrast agents has been abandoned almost completely because a hyperintense lumen does not enable a clear differentiation with inflammatory parietal enhancement.A negative agent is a substance that produces a low signal intensity on T1-and T2-weighted sequences. These substances induce local inhomogeneity in the magnetic field that affects T1 and T2 relaxation time. T2 effects predominate and are caused by spin dephasing with a consequent loss of signal intensity. Negative contrast agents include perfluorooctyl bromide [17] , iron oxides [15,18] , and oral magnetic particles [14,15] . Barium sulfate, if used at high concentrations, can be considered a negative contrast agent [19] . Negative contrast agents are more favorable if hyperintense signal of the bowel wall and the surrounding fat tissue signs of acute inflammation have to be detected on T2-weighted sequences [15] . However, magnetic susceptibility on gradient echo sequences may alter image quality on breath-held T1-weighted images.The term "biphasic" recently was introduced to define those substances that show different signal intensities depending on different sequences [20] . The first group (hyperintense signal on T1-weighted images and hypointense signal on T2-weighted images) included manganese and substances that contain manganese, and gadolinium chelates, w...

show abstract

Section: Sequencesmentioning

confidence: 99%

“…Chronic inflammatory disease, and in particular, CD, represents the most common application of MRI of small bowel [1][2][3][4][5]8,9,15,[28][29][30][31][32][33][34][35]38] .…”

Section: Inflammatory Bowel Disease (Cd) (Figures 1-4)mentioning

confidence: 99%

Section: Assessment Of Disease Activitymentioning

confidence: 99%

Section: Imaging Findingsmentioning

confidence: 99%

See 2 more Smart Citations

Updating magnetic resonance imaging of small bowel: Imaging protocols and clinical indications

Zhu¹,

Xu²,

Gong³

et al. 2008

WJG

View full text Add to dashboard Cite

show abstract

“…CT and MR enterography utilize 2D CT and MR images for diagnosis. Furukawa et al reviewed the effects of preparations, contrast agents, and scanning techniques for CT and MR image-based diagnosis [6]. Many researches use MR images for diagnosis [7]- [9].…”

Section: Introductionmentioning

confidence: 99%

Automated Ulcer Detection Method from CT Images for Computer Aided Diagnosis of Crohn's Disease

Oda

Kitasaka

Watanabe

et al. 2013

IEICE Trans. Inf. & Syst.

View full text Add to dashboard Cite

SUMMARYCrohn's disease commonly affects the small and large intestines. Its symptoms include ulcers and intestinal stenosis, and its diagnosis is currently performed using an endoscope. However, because the endoscope cannot pass through the stenosed parts of the intestines, diagnosis of the entire intestines is difficult. A CT image-based method is expected to become an alternative way for the diagnosis of Crohn's disease because it enables observation of the entire intestine even if stenosis exists. To achieve efficient CT image-based diagnosis, diagnostic-aid by computers is required. This paper presents an automated detection method of the surface of ulcers in the small and large intestines from fecal tagging CT images. Ulcers cause rough surfaces on the intestinal wall and consist of small convex and concave (CC) regions. We detect them by blob and inverse-blob structure enhancement filters. A roughness value is utilized to reduce the false positives of the detection results. Many CC regions are concentrated in ulcers. The roughness value evaluates the concentration ratio of the detected regions. Detected regions with low roughness values are removed by a thresholding process. The thickness of the intestinal lumen and the CT values of the surrounding tissue of the intestinal lumen are also used to reduce false positives. Experimental results using ten cases of CT images showed that our proposed method detects 70.6% of ulcers with 12.7 FPs/case. The proposed method detected most of the ulcers.

show abstract

Cross‐Sectional Imaging of Inflammatory Bowel Disease

Taylor¹,

Halligan²

2006

Challenges in Inflammatory Bowel Disease

View full text Add to dashboard Cite

Cross-sectional Imaging in Crohn Disease

Cited by 228 publications

References 37 publications

Updating magnetic resonance imaging of small bowel: Imaging protocols and clinical indications

Updating magnetic resonance imaging of small bowel: Imaging protocols and clinical indications

Automated Ulcer Detection Method from CT Images for Computer Aided Diagnosis of Crohn's Disease

Cross‐Sectional Imaging of Inflammatory Bowel Disease

Contact Info

Product

Resources

About