The 115 In(n,γ) 116m In reaction cross section at neutron energies of 1.12, 2.12, 3.12 and 4.12 MeV was determined by using an activation and off-line γ-ray spectrometric technique. The monoenergetic neutron energies of 1.12 − 4.12 MeV were generated from the 7 Li(p,n) reaction by using proton beam with energies of 3 and 4 MeV from the folded tandem ion beam accelerator (FOTIA) at Bhabha Atomic Research Centre (BARC) and with energies of 5 and 6 MeV from the Pelletron facility at Tata Institute of Fundamental Research (TIFR), Mumbai. The 197 Au(n,γ) 198 Au reaction cross-section was used as the neutron flux monitor. The 115 In(n,γ) 116m In reaction cross-sections at neutron energies of 1.12 − 4.12 MeV were compared with the literature data and were found to be in good agreement with one set of data, but not with others. The 115 In(n,γ) 116m In cross-section was also calculated theoretically by using the computer code TALYS 1.6 and was found to be slightly lower than the experimental data from the present work and the literature.