The bremsstrahlung flux-averaged cross-sections σ(Eγmax) for the photonuclear reactions 65 Cu(γ, n) 64 Cu, 63 Cu(γ, n) 62 Cu, 63 Cu(γ, 2n) 61 Cu and 63 Cu(γ, 3n) 60 Cu have been measured in the range of bremsstrahlung end-point energies Eγmax = 35-94 MeV. The experiments were performed with the electron beam from the NSC KIPT linear accelerator LUE-40 with the use of the activation and off-line γ-ray spectrometric technique. The calculation of the flux-average cross-sections σ(Eγmax) th was carried out using the cross-section σ(E) values from the TALYS1.95 code with the default options. It is shown that the experimental average cross-sections for the reactions 65 Cu(γ, n) 64 Cu, 63 Cu(γ, n) 62 Cu, 63 Cu(γ, 2n) 61 Cu are systematically higher than the theoretical estimates in the TALYS1.95 code. The obtained σ(Eγmax) supplement the data of different laboratories for the case of reactions (γ, n) and (γ, 2n). For the reaction 63 Cu(γ, 3n) 60 Cu, the values of σ(Eγmax) were measured for the first time.