In experiments on the electron linac LUE-40 of RDC “Accelerator” NSC KIPT, the flux-averaged cross-sections σ(Еγmax)exp of photonuclear reactions 100Mo(γ,n)99Mo,
27Al(γ,x) 24Na, 93Nb(γ,n)92mNb, 93Nb(γ,3n)90Nb, and 181Ta(γ,n)180gTa were measured using the γ-activation technique. The theoretical flux-average cross-sections
σ(Еmax)th were computed using the partial cross-section σ(Е) values from the TALYS1.9-1.95 codes and bremsstrahlung γ-flux calculated using GEANT4.9.2. Two different experimental setups were used in the experiments: an aluminum electron absorber and a deflecting magnet to clean the bremsstrahlung γ-flux from electrons. A
comparison of the flux-average cross-sections measured for two experimental setups was performed. The possibility of using the reactions 100Mo(γ,n)99Mo,27Al(γ,x)24Na, 93Nb(γ,n)92mNb, 93Nb(γ,3n)90Nb, and 181Ta(,n)180gTa as monitors of the bremsstrahlung γ-flux for the energy range 30…100 MeV was investigated.