Crossed molecular beam studies of proton transfer, unimolecular decay, and isotope scrambling in the reactions H2+ + H2O, H2+ + D2O, and D2+ + H2O

Hyaluronic acid is a negatively charged polysaccharide with a high degree of polydispersity that makes the separation of its oligomers extremely difficult. Through the use of columns filled with a highly viscous polyacrylamide matrix, the unit resolution of hyaluronate oligomers could be achieved, up to at least 80 kDa of mass, through capillary electrophoresis. As analytical application examples, the fractions of enzymatically or ultrasonically degraded hyaluronates were monitored through this method. Because of the very high resolving power, peaks additional to the regular oligomers can be observed that are assumed to be conformers of this regular, unbranched biopolymer.

show abstract

Electrophoretic Light Scattering Studies of Chitosans with Different Degrees of N-acetylation

Strand

et al. 2001

View full text Add to dashboard Cite

Electrostatic properties of three chitosans with fractions of N-acetylated units (F(A)) of 0.01, 0.13 and 0.49 were examined by electrophoretic light-scattering technique (ELS) and (1)H NMR spectroscopy. From the dependency of mean electrophoretic mobilities on pH, the pK(a) values were calculated. Despite their large differences in chemical composition, all chitosans had similar pK(a) values of 6.5-6.6. All chitosans also showed the same polyelectrolyte behavior when apparent pK(a) values were calculated according to Katchalsky and plotted as a function of the degree of ionization alpha. The intrinsic pK(a) values (pK(0)) extrapolated to zero charge were about 9. The results derived from an independent (1)H NMR study of the same chitosan samples showed no effect of F(A) on titration behavior of chitosan, confirming the results obtained by ELS.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Crossed molecular beam studies of proton transfer, unimolecular decay, and isotope scrambling in the reactions H2+ + H2O, H2+ + D2O, and D2+ + H2O

Cited by 14 publications

References 5 publications

Ion-molecule reactions: Collision dynamics and energy partitioning

Ion-molecule reactions: Collision dynamics and energy partitioning

High-Resolution Studies of Hyaluronic Acid Mixtures through Capillary Gel Electrophoresis

Electrophoretic Light Scattering Studies of Chitosans with Different Degrees of N-acetylation

Contact Info

Product

Resources

About