Crosslinking of Poly(L-lactide) by γ-Irradiation

Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial

“…On the other hand, radiation processing and commercially dominated sterilization process by high-energy radiation are successfully utilized for modification and sterilization of sensitive PLLA (Nijenhius et al, 1996;Nijsen et al, Isama and Tsuchiya, 2002;Loo et al, 2005). The dominant effect of irradiation on PLLA is chain scission, but there are some recent reports concerning irradiation cross linking by introducing cross linking agent such as triallyl isocyanurate (TAIC) (Mitomo et al, 2005;Jin et al, 2002). However, because of excellent penetration characteristics of ionizing radiation, radiation sterilization eliminates problems which may appear with other sterilization methods like high sterilization temperature, need for quarantine, problems associated with residuals and ethylene oxide gas penetration, uniformity of sterilization, etc.…”

Silane crosslinking of poly(lactic acid): The effect of simultaneous hydrolytic degradation

“…Crosslinking could be a good strategy to overcome this disadvantage. Radiation and chemical crosslinking are two well-known methods for osslinking and have been reported in the literatures [7][8][9][10][11][12][13][14][15].…”

Electron-beam irradiation on poly(propylene carbonate) in the presence of polyfunctional monomers

“…The crosslinked PBS containing 1% TMAIC had a higher glass transition temperature (T g ) than the original PBS, which greatly improved its thermal stability. Hyon et al observed that triallyl isocyanurate (TAIC) induced crosslinking of polylactic acid at low concentration (1.0 wt%) under low g-irradiation dose (25 kGy) [28]. The gel fraction of crosslinked PLLA increased with TAIC concentration and g-ray dose.…”