Crosstalk and gene expression in microorganisms under metals stress

Sharma, Pooja; Bano, Ambreen; Nadda, Ashok Kumar; Sharma, Swati; Varjani, Sunita; Singh, Surendra

doi:10.1007/s00203-022-02978-8

Cited by 10 publications

(5 citation statements)

References 191 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Phytochelatins (PCs) are a set of heavy-metal-binding peptides which consists mainly of the amino acids Glu, Cys, and Gly, where the latter two are linked and result in the formation of g-Glu-Cys dipeptides [ 110 , 131 ]. PCs were discovered first by Hayashi and his group (1981) [ 132 ] as Cd-binding complexes in fission yeast, Schizosaccharomyces pombe , exposed to Cd 2 + , and were named as “cadystins” [ 132 , 133 , 134 ], and then in cell suspension cultures of the higher plant Rauvolfia serpentina after exposure to Cd [ 126 , 131 , 135 ]. Afterwards, PCs were identified in all plant species, and investigated as well as in algae, fungi, and diatoms [ 126 , 136 ].…”

Section: Bryophytes and Heavy Metalsmentioning

confidence: 99%

“…Afterwards, PCs were identified in all plant species, and investigated as well as in algae, fungi, and diatoms [ 126 , 136 ]. PCs are synthesized inductively by exposure not only to Cd, but also to other heavy metals such as Hg, Cu, Zn, Pb and Ni [ 110 , 131 ]. Glutathione, hydroxymethyl-glutathione, and G-glutamylcysteine were reported as the major precursors for PC synthesis [ 131 , 137 , 138 ] through the enzyme PC synthase (PCS) ( Figure 2 ); the activation of this enzyme requires a post-translational modification which can be induced by the toxic metals [ 131 , 138 ].…”

Section: Bryophytes and Heavy Metalsmentioning

confidence: 99%

“…PCs are synthesized inductively by exposure not only to Cd, but also to other heavy metals such as Hg, Cu, Zn, Pb and Ni [ 110 , 131 ]. Glutathione, hydroxymethyl-glutathione, and G-glutamylcysteine were reported as the major precursors for PC synthesis [ 131 , 137 , 138 ] through the enzyme PC synthase (PCS) ( Figure 2 ); the activation of this enzyme requires a post-translational modification which can be induced by the toxic metals [ 131 , 138 ]. PC synthase catalyses the transpeptidation of the γ-Glu-Cys moiety of GSH either onto a second GSH molecule to form PC ( n =2) or onto a PC molecule to produce a PC ( n +1) oligomer [ 139 ].…”

Section: Bryophytes and Heavy Metalsmentioning

confidence: 99%

See 2 more Smart Citations

Non-Protein Thiol Compounds and Antioxidant Responses Involved in Bryophyte Heavy-Metal Tolerance

Salbitani

Maresca

Cianciullo

et al. 2023

IJMS

View full text Add to dashboard Cite

Heavy-metal pollution represents a problem which has been widely discussed in recent years. The biological effects of heavy metals have been studied in both animals and plants, ranging from oxidative stress to genotoxicity. Plants, above all metal-tolerant species, have evolved a wide spectrum of strategies to counteract exposure to toxic metal concentrations. Among these strategies, the chelation and vacuolar sequestration of heavy metals are, after cell-wall immobilization, the first line of defence that prevent heavy metals from interacting with cell components. Furthermore, bryophytes activate a series of antioxidant non-enzymatic and enzymatic responses to counteract the effects of heavy metal in the cellular compartments. In this review, the role of non-protein thiol compounds and antioxidant molecules in bryophytes will be discussed.

show abstract

Section: Bryophytes and Heavy Metalsmentioning

confidence: 99%

Section: Bryophytes and Heavy Metalsmentioning

confidence: 99%

Section: Bryophytes and Heavy Metalsmentioning

confidence: 99%

See 1 more Smart Citation

Non-Protein Thiol Compounds and Antioxidant Responses Involved in Bryophyte Heavy-Metal Tolerance

Salbitani

Maresca

Cianciullo

et al. 2023

IJMS

View full text Add to dashboard Cite

show abstract

“…Microbial organic fertilizer contains a high amount of plant active substances and enzymes, and it is rich in organic matter and various microelements. Microbial organic fertilizer has the function of increasing soil nutrients, improving soil physical and chemical properties, enhancing crop yield and quality, and neutralizing or decomposing toxic substances [13][14][15][16]. The microorganisms can remove heavy metal in soil through interactions such as chelation, complex formation, covalent adsorption and ion exchange [17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Microbial Compound Fertilizer on the Heavy Metal Binding Forms and Enzyme Activity in Soil

Zhao,

Huang,

Liang

et al. 2024

Processes

View full text Add to dashboard Cite

Nowadays, heavy metal pollution in soil caused by human production activities is increasingly serious. The heavy metal ions in soil inhibit plant growth and endanger human health as they can disrupt the physicochemical properties of soil. However, the elimination of heavy metals in soil is so difficult that more and more researchers are studying effective soil conditioners. The negatively charged groups in microbial communities can bind with heavy metal ions in the soil to remove them. In this paper, Cr- and Cd-polluted soils were used to simulate heavy-metal-polluted soil, and microbial compound fertilizer (MOF) was used as a soil conditioner for removing Cr and Cd in soil. The effects of different additive amounts of MOF on the physicochemical properties, the concentration of metal binding forms in soil and the enzyme activity of soil were investigated. The results showed that when the addition amount of fertilizer was 10%, the improvement effect on Cr- and Cd-polluted soils was the best. Compared with polluted soils without MOF addition, the physicochemical properties of MOF-treated polluted soils improved significantly, the concentration of effective forms of heavy metals decreased significantly, and the concentration of organic and residual forms as well as soil enzyme activity increased significantly. This indicates that the addition of MOF can increase the activity of soil microbial communities and soil fertility, and has the ability to remediate heavy-metal-polluted soil. MOF is expected to become an efficient soil conditioner for heavy metals.

show abstract

“…Bacteria can modulate their gene expression profile and adapt their metabolism to resist toxic agents [ 6 , 7 ]. This regulation operates at two levels, either transcriptional or post-transcriptional [ 5 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Role of the Bacterial Amyloid-like Hfq in Fluoroquinolone Fluxes

Turbant,

Esnouf,

Rosaz

et al. 2023

Microorganisms

View full text Add to dashboard Cite

Due to their two-cell membranes, Gram-negative bacteria are particularly resistant to antibiotics. Recent investigations aimed at exploring new target proteins involved in Gram-negative bacteria adaptation helped to identify environmental changes encountered during infection. One of the most promising approaches in finding novel targets for antibacterial drugs consists of blocking noncoding RNA-based regulation using the protein cofactor, Hfq. Although Hfq is important in many bacterial pathogens, its involvement in antibiotics response is still unclear. Indeed, Hfq may mediate drug resistance by regulating the major efflux system in Escherichia coli, but it could also play a role in the influx of antibiotics. Here, using an imaging approach, we addressed this problem quantitatively at the single-cell level. More precisely, we analyzed how Hfq affects the dynamic influx and efflux of ciprofloxacin, an antibiotic from the group of fluoroquinolones that is used to treat bacterial infections. Our results indicated that the absence of either whole Hfq or its C-terminal domain resulted in a more effective accumulation of ciprofloxacin, irrespective of the presence of the functional AcrAB-TolC efflux pump. However, overproduction of the MicF small regulatory RNA, which reduces the efficiency of expression of the ompF gene (coding for a porin involved in antibiotics influx) in a Hfq-dependent manner, resulted in impaired accumulation of ciprofloxacin. These results led us to propose potential mechanisms of action of Hfq in the regulation of fluoroquinolone fluxes across the E. coli envelope.

show abstract

Crosstalk and gene expression in microorganisms under metals stress

Cited by 10 publications

References 191 publications

Non-Protein Thiol Compounds and Antioxidant Responses Involved in Bryophyte Heavy-Metal Tolerance

Non-Protein Thiol Compounds and Antioxidant Responses Involved in Bryophyte Heavy-Metal Tolerance

The Effect of Microbial Compound Fertilizer on the Heavy Metal Binding Forms and Enzyme Activity in Soil

Role of the Bacterial Amyloid-like Hfq in Fluoroquinolone Fluxes

Contact Info

Product

Resources

About