Crosstalk between lncRNAs and Wnt/β-catenin signaling pathways in lung cancers: From cancer progression to therapeutic response

Wu, Ting; Dong, YiRan; Yang, XinZhi; Mo, Liang; You, Yong

doi:10.1016/j.ncrna.2024.02.013

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Insights Into the Exosomal Lncrnas And Circrnas1

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2024

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“…Emerging evidence indicates that exosomal lncRNAs and circRNAs are influential modulators of lung cancer drug resistance. By transporting diverse drug-resistant biomolecules, these exosomal non-coding RNAs play critical roles in lung cancer development, metastatic recurrence, and chemotherapy resistance [ 42 , 79 ]. For instance, exosomal lncRNA FOXD3-AS1 enhances ELAVL1 expression, activating the PI3K/Akt pathway to fortify lung cancer cell proliferation, invasion, and 5-fluorouracil resistance [ 58 ].…”

Section: Insights Into the Exosomal Lncrnas And Circrnasmentioning

confidence: 99%