2021
DOI: 10.1371/journal.pcbi.1009463
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Crowdsourcing biocuration: The Community Assessment of Community Annotation with Ontologies (CACAO)

Abstract: Experimental data about gene functions curated from the primary literature have enormous value for research scientists in understanding biology. Using the Gene Ontology (GO), manual curation by experts has provided an important resource for studying gene function, especially within model organisms. Unprecedented expansion of the scientific literature and validation of the predicted proteins have increased both data value and the challenges of keeping pace. Capturing literature-based functional annotations is l… Show more

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Cited by 7 publications
(10 citation statements)
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“…Peer review of the annotations by the students themselves would provide a more efficient biocuration project model, and this has been achieved, by a group at Texas A&M, through the establishment of an annotation competition. 12 As significant resources are needed to train new biocurators before they are able to work independently, 29 biocuration projects, such as the ones provided at UCL, provide substantial initial training for students as biocurators, Indeed, three of our respondents are currently working as biocurators after completion of their projects.…”
Section: Discussionmentioning
confidence: 99%
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“…Peer review of the annotations by the students themselves would provide a more efficient biocuration project model, and this has been achieved, by a group at Texas A&M, through the establishment of an annotation competition. 12 As significant resources are needed to train new biocurators before they are able to work independently, 29 biocuration projects, such as the ones provided at UCL, provide substantial initial training for students as biocurators, Indeed, three of our respondents are currently working as biocurators after completion of their projects.…”
Section: Discussionmentioning
confidence: 99%
“…However, several students were motivated to volunteer to participate in future curation projects because of the satisfaction of knowing that their annotations were being shared and would be of benefit to the wider scientific community. Unfortunately, there are only a very few examples of successful community biocuration efforts 8 , 10 , 12 , 41 , 42 and, therefore, the opportunities for the wider scientific community to contribute to this need are limited. One of the rate limiting factors in community curation is checking the accuracy of the submitted annotations by expert biocurators.…”
Section: Discussionmentioning
confidence: 99%
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