Crowned dens syndrome

Inokuchi, Ryota; Ohshima, Kazuma; Yamamoto, Miyuki; Fukuda, Tatsuma; Nakamura, Kensuke

doi:10.1016/j.spinee.2015.03.022

Cited by 5 publications

(4 citation statements)

References 7 publications

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“…However, nine subjects with CDS in our study II included five females and four males, which did not agree with the previous two studies [10,24]. Further, according to case reports accumulated by our Pubmed search, 11 of 22 cases with CDS were women, challenging a female predominance in CDS [2,4,5,7,8,[10][11][12][13][14][15][16][17][18][19][20][21][22][23][24]. To confirm a female predominance in CDS, further studies, preferably with a greater number of CDS subjects, are needed.…”

Section: Yoshikawa Et Alcontrasting

confidence: 67%

“…According to our Pubmed search (reports written in English), the mean age in patients with CDS was 78.1 years old (11 males and 11 females), supporting a significant association between CDS and old age [2,4,5,7,8,[11][12][13][14][15][16][17][18][19][20][21][22][23].…”

Section: Yoshikawa Et Almentioning

confidence: 65%

“…The computed tomography (CT) is the gold standard in identifying CDS, as it is able to depict the shape and site of calcification, and CT shows radiopaque densities surrounding the top and sides of the odontoid process in a crown-like distribution [1][2][3][4]. Characteristic CT findings have been reported [5][6][7][8]. The diagnosis of CDS may be based on clinical symptoms such as neck pain, neck stiffness and fever, and the calcifications surrounding the top and sides of the odontoid process which are detected by CT, and increased levels of inflammatory markers such as erythrocyte sedimentation rate and C-reactive protein (CRP) [1,6,9,10].…”

Section: Introductionmentioning

confidence: 99%

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Incidence, Age and Gender of Subjects With the Calcium Pyrophosphate Deposition Around the Dens, and Clinical Characteristics of Patients With Crowned Dens Syndrome

et al. 2016

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Section: Yoshikawa Et Alcontrasting

confidence: 67%

Section: Yoshikawa Et Almentioning

confidence: 65%

Section: Introductionmentioning

confidence: 99%

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Incidence, Age and Gender of Subjects With the Calcium Pyrophosphate Deposition Around the Dens, and Clinical Characteristics of Patients With Crowned Dens Syndrome

et al. 2016

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“…Bouvet et al [1] first reported a case of acute neck pain in association with periodontoid calcification; this condition is called as “crowned dens syndrome.” This association of periodontoid calcification and severe acute neck pain was reconfirmed by Goto et al [2] in a detailed review of the clinical records of 40 patients. Several studies also reported positive associations between acute neck pain and periodontoid calcification or crowned dens syndrome, as per CT diagnosis [1,2,8-12]. However, calcification is not always symptomatic.…”

Section: Discussionmentioning

confidence: 99%

Age-Related Prevalence of Periodontoid Calcification and Its Associations with Acute Cervical Pain

et al. 2018

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Study DesignProspective study.PurposeTo assess the prevalence of periodontoid calcification and its associations with acute cervical pain.Overview of LiteratureCalcium pyrophosphate dihydrate (CPPD) deposition disease is a common rheumatological disorder that occurs especially in elderly patients. Although CPPD crystals induce acute arthritis, these crystals are not usually symptomatic. Calcification surrounding the odontoid process (periodontoid calcification) has been reported to induce inflammation, resulting in acute neck pain. This disease is called crowned dens syndrome. Whether calcification induces inflammation or whether the crystals are symptomatic remains unclear.MethodsThe prevalence of periodontoid calcification at the atlas transverse ligament was examined by computed tomography of the upper cervical spine in patients suspected of brain disease but no cervical pain (control group, n=296), patients with pseudogout of the peripheral joints but no cervical pain (arthritis group, n=41), and patients with acute neck pain (neck pain group, n=22). Next, the correlation between the prevalence of periodontoid calcification and symptoms was analyzed.ResultsIn the control group, 40 patients (13.5%) showed periodontoid calcification with no significant difference in the prevalence with gender. The prevalence of calcification increased significantly with age (p=0.002). In the arthritis group, 26 patients (63.4%) reported periodontoid calcification. In the neck pain group, 14 patients (63.6%) reported periodontoid calcification. Multiple logistic regression analysis by age and group revealed that higher age, inclusion in the arthritis group, and inclusion in the neck pain group significantly affected the prevalence of calcification.ConclusionsOur results cumulatively suggest that periodontoid calcification is an aging-related reaction and that calcification per se does not always cause neck pain. Periodontoid calcification was observed more frequently in patients with pseudogout of the peripheral joints and in those with acute neck pain than in asymptomatic control patients.

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Spinal Manifestations of Systemic Disease

Dodson¹,

Koontz

2019

Radiologic Clinics of North America

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Crowned dens syndrome

Cited by 5 publications

References 7 publications

Incidence, Age and Gender of Subjects With the Calcium Pyrophosphate Deposition Around the Dens, and Clinical Characteristics of Patients With Crowned Dens Syndrome

Incidence, Age and Gender of Subjects With the Calcium Pyrophosphate Deposition Around the Dens, and Clinical Characteristics of Patients With Crowned Dens Syndrome

Age-Related Prevalence of Periodontoid Calcification and Its Associations with Acute Cervical Pain

Spinal Manifestations of Systemic Disease

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